4B3U
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0005829 | cellular_component | cytosol |
| A | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000271 | biological_process | polysaccharide biosynthetic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000271 | biological_process | polysaccharide biosynthetic process |
| D | 0005829 | cellular_component | cytosol |
| D | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NWL A 400 |
| Chain | Residue |
| A | LEU45 |
| A | HOH2201 |
| A | GLY115 |
| A | ARG219 |
| A | ALA251 |
| A | GLU255 |
| A | ILE256 |
| A | ARG259 |
| A | GLN260 |
| A | GOL1295 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1294 |
| Chain | Residue |
| A | HIS116 |
| A | ARG219 |
| A | GLY220 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1295 |
| Chain | Residue |
| A | SER41 |
| A | THR42 |
| A | LEU45 |
| A | TYR113 |
| A | PHE118 |
| A | ALA251 |
| A | NWL400 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MES A 1296 |
| Chain | Residue |
| A | GLY154 |
| A | ALA156 |
| A | VAL214 |
| A | HOH2141 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NWL B 400 |
| Chain | Residue |
| B | LEU45 |
| B | ARG219 |
| B | ALA251 |
| B | GLU255 |
| B | ILE256 |
| B | ARG259 |
| B | HOH2176 |
| B | HOH2177 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1294 |
| Chain | Residue |
| B | HIS116 |
| B | ARG219 |
| B | GLY220 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MES B 1295 |
| Chain | Residue |
| B | PHE150 |
| B | GLY154 |
| B | LYS155 |
| B | ALA156 |
| B | LEU212 |
| B | VAL214 |
| B | ILE216 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NWL C 400 |
| Chain | Residue |
| C | LEU45 |
| C | ARG219 |
| C | ALA251 |
| C | GLU255 |
| C | ILE256 |
| C | GOL1295 |
| C | HOH2085 |
| C | HOH2173 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1294 |
| Chain | Residue |
| C | HIS116 |
| C | ARG219 |
| C | GLY220 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 1295 |
| Chain | Residue |
| C | TYR38 |
| C | THR42 |
| C | LEU45 |
| C | TYR113 |
| C | PHE118 |
| C | ALA251 |
| C | NWL400 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1296 |
| Chain | Residue |
| C | HIS229 |
| C | LEU232 |
| C | LEU233 |
| D | PRO29 |
| D | TYR31 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES C 1297 |
| Chain | Residue |
| C | PHE150 |
| C | GLY154 |
| C | ALA156 |
| C | VAL214 |
| C | ILE216 |
| C | HOH2151 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NWL D 400 |
| Chain | Residue |
| D | LEU45 |
| D | ARG219 |
| D | ALA251 |
| D | GLU255 |
| D | ILE256 |
| D | GLN260 |
| D | GOL1295 |
| D | HOH2065 |
| D | HOH2118 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1294 |
| Chain | Residue |
| D | HIS116 |
| D | GLY220 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 1295 |
| Chain | Residue |
| D | TYR38 |
| D | SER41 |
| D | THR42 |
| D | LEU45 |
| D | TYR113 |
| D | PHE118 |
| D | ALA251 |
| D | NWL400 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MES D 1296 |
| Chain | Residue |
| D | GLY154 |
| D | ALA156 |
| D | VAL214 |
