4B0C

Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa in complex with 3-(pentylthio)-4H-1,2,4-triazole

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0006636	biological_process	unsaturated fatty acid biosynthetic process
A	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
A	0016829	molecular_function	lyase activity
A	0016853	molecular_function	isomerase activity
A	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
A	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
B	0005737	cellular_component	cytoplasm
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0006636	biological_process	unsaturated fatty acid biosynthetic process
B	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
B	0016829	molecular_function	lyase activity
B	0016853	molecular_function	isomerase activity
B	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
B	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
C	0005737	cellular_component	cytoplasm
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0006636	biological_process	unsaturated fatty acid biosynthetic process
C	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
C	0016829	molecular_function	lyase activity
C	0016853	molecular_function	isomerase activity
C	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
C	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
D	0005737	cellular_component	cytoplasm
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0006636	biological_process	unsaturated fatty acid biosynthetic process
D	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
D	0016829	molecular_function	lyase activity
D	0016853	molecular_function	isomerase activity
D	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
D	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
E	0005737	cellular_component	cytoplasm
E	0006629	biological_process	lipid metabolic process
E	0006631	biological_process	fatty acid metabolic process
E	0006633	biological_process	fatty acid biosynthetic process
E	0006636	biological_process	unsaturated fatty acid biosynthetic process
E	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
E	0016829	molecular_function	lyase activity
E	0016853	molecular_function	isomerase activity
E	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
E	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE C9H A 501

Chain	Residue
A	HIS70
A	GLY79
A	GLY115
A	HOH2002
B	TRP87
B	ALA105
B	PHE171

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE C9H B 501

Chain	Residue
A	ALA105
A	HOH2003
B	MET77
A	GLY103
A	ARG104

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE C9H C 501

Chain	Residue
C	MET77
C	GLY79
D	ALA105
D	PHE171

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE C9H D 501

Chain	Residue
C	ASP84
C	TRP87
C	ALA105
D	HIS70
D	MET77
D	GLY79
D	TYR155

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE C9H E 501

Chain	Residue
E	HIS70
E	MET77
E	GLY79
E	ALA105
E	GLY115
E	TYR155

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	HIS70
B	HIS70
C	HIS70
D	HIS70
E	HIS70

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