Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1385 |
| Chain | Residue |
| A | GLY34 |
| A | SER35 |
| A | 32D1391 |
| A | HOH2355 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1386 |
| Chain | Residue |
| A | LEU188 |
| A | TRP189 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 1387 |
| Chain | Residue |
| A | ILE102 |
| A | THR103 |
| A | SER105 |
| A | PHE109 |
| A | ALA43 |
| A | PRO44 |
| A | HIS45 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1388 |
| Chain | Residue |
| A | LYS246 |
| A | SER247 |
| A | ALA250 |
| A | HOH2245 |
| A | HOH2248 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1389 |
| Chain | Residue |
| A | THR94 |
| A | ARG96 |
| A | HOH2161 |
| A | HOH2322 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1390 |
| Chain | Residue |
| A | VAL141 |
| A | THR144 |
| A | HOH2159 |
| A | HOH2160 |
| A | HOH2162 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 32D A 1391 |
| Chain | Residue |
| A | GLY11 |
| A | GLN12 |
| A | GLY13 |
| A | LEU30 |
| A | ASP32 |
| A | GLY34 |
| A | SER35 |
| A | ASN37 |
| A | TYR71 |
| A | GLN73 |
| A | TRP76 |
| A | PHE108 |
| A | ILE110 |
| A | ILE118 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | ACT1385 |
| A | HOH2024 |
| A | HOH2223 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17425515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19011241","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
