4AY5
Human O-GlcNAc transferase (OGT) in complex with UDP and glycopeptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006493 | biological_process | protein O-linked glycosylation |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0006493 | biological_process | protein O-linked glycosylation |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0006493 | biological_process | protein O-linked glycosylation |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0006493 | biological_process | protein O-linked glycosylation |
| D | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GlcNAc) serine => ECO:0000269|PubMed:22307082, ECO:0000269|PubMed:28939839 |
| Chain | Residue | Details |
| I | SER7 | |
| J | SER7 | |
| K | SER7 | |
| L | SER7 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23103939, ECO:0007744|PDB:4GYW |
| Chain | Residue | Details |
| A | GLN849 | |
| B | CYS911 | |
| B | GLY930 | |
| B | THR935 | |
| C | GLN849 | |
| C | ALA852 | |
| C | GLN906 | |
| C | CYS911 | |
| C | GLY930 | |
| C | THR935 | |
| D | GLN849 | |
| A | ALA852 | |
| D | ALA852 | |
| D | GLN906 | |
| D | CYS911 | |
| D | GLY930 | |
| D | THR935 | |
| A | GLN906 | |
| A | CYS911 | |
| A | GLY930 | |
| A | THR935 | |
| B | GLN849 | |
| B | ALA852 | |
| B | GLN906 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by AMPK => ECO:0000269|PubMed:24563466, ECO:0000269|PubMed:37541260 |
| Chain | Residue | Details |
| A | ASP454 | |
| B | ASP454 | |
| C | ASP454 | |
| D | ASP454 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P56558 |
| Chain | Residue | Details |
| A | LYS989 | |
| B | LYS989 | |
| C | LYS989 | |
| D | LYS989 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; by autocatalysis => ECO:0000269|PubMed:27713473 |
| Chain | Residue | Details |
| A | GLN399 | |
| B | GLN399 | |
| C | GLN399 | |
| D | GLN399 |
