4AXG

Structure of eIF4E-Cup complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000339	molecular_function	RNA cap binding
A	0000340	molecular_function	RNA 7-methylguanosine cap binding
A	0000932	cellular_component	P-body
A	0003723	molecular_function	RNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0006417	biological_process	regulation of translation
A	0016070	biological_process	RNA metabolic process
A	0016281	cellular_component	eukaryotic translation initiation factor 4F complex
A	0016604	cellular_component	nuclear body
A	0031370	molecular_function	eukaryotic initiation factor 4G binding
A	0031594	cellular_component	neuromuscular junction
A	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
A	0071598	cellular_component	neuronal ribonucleoprotein granule
A	0097482	cellular_component	muscle cell postsynaptic specialization
B	0000339	molecular_function	RNA cap binding
B	0000340	molecular_function	RNA 7-methylguanosine cap binding
B	0000932	cellular_component	P-body
B	0003723	molecular_function	RNA binding
B	0003743	molecular_function	translation initiation factor activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006413	biological_process	translational initiation
B	0006417	biological_process	regulation of translation
B	0016070	biological_process	RNA metabolic process
B	0016281	cellular_component	eukaryotic translation initiation factor 4F complex
B	0016604	cellular_component	nuclear body
B	0031370	molecular_function	eukaryotic initiation factor 4G binding
B	0031594	cellular_component	neuromuscular junction
B	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
B	0071598	cellular_component	neuronal ribonucleoprotein granule
B	0097482	cellular_component	muscle cell postsynaptic specialization

Functional Information from PROSITE/UniProt

site_id	PS00813
Number of Residues	24
Details	IF4E Eukaryotic initiation factor 4E signature. DYslFKknIrPmWEDaankqGGRW

Chain	Residue	Details
A	ASP123-TRP146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P06730","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Motif: {"description":"YXXXXLphi motif 1","evidences":[{"source":"PubMed","id":"14685270","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14723848","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Motif: {"description":"YXXXXLphi motif 2","evidences":[{"source":"PubMed","id":"14685270","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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