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Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4AWG

Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication
B	0003723	molecular_function	RNA binding
B	0039694	biological_process	viral RNA genome replication
C	0003723	molecular_function	RNA binding
C	0039694	biological_process	viral RNA genome replication
D	0003723	molecular_function	RNA binding
D	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 401

Chain	Residue
A	ARG84
A	TRP88
A	PHE105
A	LEU106
A	CI3801

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 402

Chain	Residue
A	THR151
A	ARG179
A	TRP188
A	ARG192

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 403

Chain	Residue
A	GLU31
A	THR32
A	ASN33
A	LYS34

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 404

Chain	Residue
A	THR123
A	ARG124
A	ARG125

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CI3 A 801

Chain	Residue
A	GLU23
A	TYR24
A	HIS41
A	GLU80
A	ARG84
A	ASP108
A	GLU119
A	ILE120
A	TYR130
A	LYS134
A	SO4401
A	MN901
A	MN902
A	HOH2013
A	HOH2016

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 901

Chain	Residue
A	HIS41
A	ASP108
A	GLU119
A	ILE120
A	CI3801

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 902

Chain	Residue
A	GLU80
A	ASP108
A	CI3801
A	HOH2013

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 401

Chain	Residue
B	ARG84
B	TRP88
B	PHE105
B	LEU106
B	CI3801

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 402

Chain	Residue
B	ARG179
B	TRP188
B	ARG192

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 403

Chain	Residue
B	GLU31
B	THR32
B	ASN33
B	LYS34

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 404

Chain	Residue
B	THR123
B	ARG124
B	ARG125
B	TYR130

site_id	BC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE CI3 B 801

Chain	Residue
B	GLU23
B	TYR24
B	LYS34
B	ALA37
B	HIS41
B	GLU80
B	ARG84
B	ASP108
B	GLU119
B	ILE120
B	TYR130
B	LYS134
B	SO4401
B	MN901
B	MN902
B	HOH2014
B	HOH2017

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 901

Chain	Residue
B	HIS41
B	ASP108
B	GLU119
B	ILE120
B	CI3801

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 902

Chain	Residue
B	HIS41
B	GLU80
B	ASP108
B	CI3801
B	HOH2012
B	HOH2014

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 401

Chain	Residue
C	ARG84
C	PHE105
C	LEU106
C	CI3801

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 402

Chain	Residue
C	ARG179
C	TRP188
C	ARG192

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 403

Chain	Residue
C	GLU31
C	THR32
C	ASN33
C	LYS34

site_id	BC9
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CI3 C 801

Chain	Residue
C	GLU80
C	ARG82
C	LEU106
C	ASP108
C	GLU119
C	ILE120
C	LYS134
C	SO4401
C	MN901
C	MN902
C	HOH2017
C	ALA20
C	GLU23
C	TYR24
C	HIS41

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 901

Chain	Residue
C	HIS41
C	ASP108
C	GLU119
C	ILE120
C	CI3801

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN C 902

Chain	Residue
C	GLU80
C	ASP108
C	CI3801
C	HOH2017

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 401

Chain	Residue
D	PHE105
D	LEU106
D	CI3801
D	HOH2013
D	HOH2015

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 402

Chain	Residue
D	ARG179
D	TRP188
D	ARG192

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 403

Chain	Residue
D	GLU31
D	THR32
D	ASN33
D	LYS34
D	SER194

site_id	CC6
Number of Residues	16
Details	BINDING SITE FOR RESIDUE CI3 D 801

Chain	Residue
D	GLU23
D	TYR24
D	GLU26
D	ILE38
D	HIS41
D	GLU80
D	ARG84
D	ASP108
D	GLU119
D	ILE120
D	LYS134
D	SO4401
D	MN901
D	MN902
D	HOH2011
D	HOH2014

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN D 901

Chain	Residue
D	HIS41
D	ASP108
D	GLU119
D	ILE120
D	CI3801
D	MN902

site_id	CC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN D 902

Chain	Residue
D	GLU80
D	ASP108
D	CI3801
D	MN901
D	HOH2011
D	HOH2014

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"source":"PubMed","id":"22876177","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27510745","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22876177","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26976575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27510745","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29215062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29691337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29941893","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30351002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31536340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36603507","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36655124","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38190441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CGV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CZN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D42","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D8U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DBS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EGA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VP8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W3I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W7U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WG9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E4C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7K0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ML8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MPF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N47","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N55","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N68","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7V04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CTF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DAL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DHN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T67","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8VGZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22876177","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26976575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27510745","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29215062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29691337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29941893","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30351002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31536340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36603507","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36655124","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38190441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D42","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D8U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EGA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W3I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WAP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WG9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E4C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7K0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ML8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MPF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N47","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N55","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N68","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7V04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CTF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DAL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DHN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T67","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8VGZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22876177","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27510745","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29215062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29691337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29941893","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30351002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31536340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36603507","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36655124","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38190441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D42","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D8U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EGA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W3I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WAP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WG9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E4C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7K0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ML8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MPF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N47","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N55","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N68","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7V04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CTF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DAL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DHN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T67","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T6Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8T94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8VGZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22876177","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26976575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27510745","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29215062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29691337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29941893","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30351002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31536340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36603507","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36655124","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38190441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CGV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D42","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EGA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VP8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W3I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W7U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WAP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E4C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7K0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ML8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MPF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N47","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N55","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N68","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7V04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CTF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DAL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DHN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DJV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Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22876177","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26976575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27510745","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29215062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29691337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29941893","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30351002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31536340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36603507","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36655124","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38190441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AWM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CGV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CZN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D42","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D8U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DBS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EGA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VP8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VPX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W3I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W7U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WAP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WE9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WG9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E3P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E4C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E6X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7K0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ML8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MPF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N47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Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	45
Details	Motif: {"description":"Nuclear localization signal 1 (NLS1)","evidences":[{"source":"UniProtKB","id":"P03433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

246031

PDB entries from 2025-12-10

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