4AW4
Engineered variant of Listeria monocytogenes InlB internalin domain with an additional leucine rich repeat inserted
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1343 |
| Chain | Residue |
| B | ASN104 |
| B | SER106 |
| B | HOH2056 |
| C | ASN104 |
| C | SER106 |
| C | ASN128 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1343 |
| Chain | Residue |
| A | SER287 |
| A | LEU288 |
| A | LYS302 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1344 |
| Chain | Residue |
| A | ASP222 |
| A | ARG246 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1345 |
| Chain | Residue |
| A | HIS241 |
| A | CYS264 |
| A | LEU265 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1346 |
| Chain | Residue |
| A | SER295 |
| A | ASP296 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1347 |
| Chain | Residue |
| A | VAL183 |
| A | HIS184 |
| A | PRO186 |
| A | ARG206 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1344 |
| Chain | Residue |
| B | VAL183 |
| B | PRO186 |
| B | ARG206 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1343 |
| Chain | Residue |
| C | GLU151 |
| C | HIS173 |
| C | HOH2060 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1345 |
| Chain | Residue |
| B | GLU151 |
| B | HIS173 |
| B | HOH2080 |
| B | HOH2089 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1348 |
| Chain | Residue |
| A | GLU151 |
| A | HIS173 |
| A | HOH2069 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1349 |
| Chain | Residue |
| A | ASN104 |
| A | ASN104 |
| A | SER106 |
| A | SER106 |
| A | PHE126 |
| A | ASN128 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1350 |
| Chain | Residue |
| A | LYS239 |
| A | SER261 |
| A | HIS334 |
| A | HOH2112 |
| A | HOH2114 |
| C | THR71 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1351 |
| Chain | Residue |
| A | THR71 |
| A | ASN73 |
| A | HOH2129 |
| C | SER261 |
| C | HIS334 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 1344 |
| Chain | Residue |
| C | GLN219 |
| C | HIS241 |
| C | GLU263 |
| C | HOH2085 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1345 |
| Chain | Residue |
| C | GLN272 |
| C | GLN272 |
| C | SER273 |
| C | SER273 |
| C | ASN274 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1346 |
| Chain | Residue |
| B | THR202 |
| B | VAL203 |
| B | SER205 |
| B | ARG206 |
| B | HOH2099 |
| B | HOH2188 |
| C | ASP285 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 1352 |
| Chain | Residue |
| A | HIS241 |
| A | GLU263 |
| A | HOH2090 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 1347 |
| Chain | Residue |
| B | HIS241 |
| B | GLU263 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1348 |
| Chain | Residue |
| B | THR71 |
| B | ASN73 |
| B | SER261 |
| B | HIS334 |
| B | HOH2147 |
| B | HOH2149 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1353 |
| Chain | Residue |
| A | ASN274 |
| B | GLN272 |
| B | SER273 |
| B | ASN274 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1349 |
| Chain | Residue |
| B | PRO323 |
| B | ARG332 |
| B | HOH2179 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1346 |
| Chain | Residue |
| C | TYR321 |
| C | ARG332 |
| C | HOH2140 |
| C | HOH2141 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1347 |
| Chain | Residue |
| B | HOH2113 |
| C | ARG246 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1354 |
| Chain | Residue |
| A | PRO323 |
| A | ARG332 |
| A | HOH2121 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1348 |
| Chain | Residue |
| C | SER287 |
| C | LEU288 |
| C | LYS302 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1350 |
| Chain | Residue |
| B | HOH2164 |
| B | SER287 |
| B | LEU288 |
| B | LYS302 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1349 |
| Chain | Residue |
| C | VAL183 |
| C | HIS184 |
| C | PRO186 |
| C | ARG206 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1351 |
| Chain | Residue |
| B | LYS131 |
| C | HIS173 |
| C | ASN195 |
| C | ASP217 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1352 |
| Chain | Residue |
| B | HIS241 |
| B | LEU265 |
| B | HOH2109 |
| site_id | DC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1355 |
| Chain | Residue |
| A | LYS131 |
| A | HIS173 |
| site_id | DC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1356 |
| Chain | Residue |
| A | PRO291 |
| A | GLU292 |
| A | ILE293 |
| A | ILE294 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1350 |
| Chain | Residue |
| B | THR208 |
| C | LYS252 |
| site_id | DC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1353 |
| Chain | Residue |
| B | SER295 |
| B | ASP296 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 66 |
| Details | Repeat: {"description":"LRR 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 54 |
| Details | Repeat: {"description":"LRR 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 63 |
| Details | Repeat: {"description":"LRR 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 69 |
| Details | Repeat: {"description":"LRR 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 54 |
| Details | Repeat: {"description":"LRR 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 69 |
| Details | Repeat: {"description":"LRR 7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10635330","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15020228","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1D0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OTO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10635330","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15020228","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1D0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OTN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 156 |
| Details | Region: {"description":"Ig-like region","evidences":[{"source":"PubMed","id":"12411480","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"15049825","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
