4ATQ
GABA-transaminase A1R958 in complex with external aldimine PLP-GABA adduct
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| D | 0042802 | molecular_function | identical protein binding |
| E | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| E | 0008483 | molecular_function | transaminase activity |
| E | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| E | 0030170 | molecular_function | pyridoxal phosphate binding |
| E | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| E | 0042802 | molecular_function | identical protein binding |
| F | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| F | 0008483 | molecular_function | transaminase activity |
| F | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| F | 0030170 | molecular_function | pyridoxal phosphate binding |
| F | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| F | 0042802 | molecular_function | identical protein binding |
| G | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| G | 0008483 | molecular_function | transaminase activity |
| G | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| G | 0030170 | molecular_function | pyridoxal phosphate binding |
| G | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| G | 0042802 | molecular_function | identical protein binding |
| H | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| H | 0008483 | molecular_function | transaminase activity |
| H | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| H | 0030170 | molecular_function | pyridoxal phosphate binding |
| H | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| H | 0042802 | molecular_function | identical protein binding |
| I | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| I | 0008483 | molecular_function | transaminase activity |
| I | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| I | 0030170 | molecular_function | pyridoxal phosphate binding |
| I | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| I | 0042802 | molecular_function | identical protein binding |
| J | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| J | 0008483 | molecular_function | transaminase activity |
| J | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| J | 0030170 | molecular_function | pyridoxal phosphate binding |
| J | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| J | 0042802 | molecular_function | identical protein binding |
| K | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| K | 0008483 | molecular_function | transaminase activity |
| K | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| K | 0030170 | molecular_function | pyridoxal phosphate binding |
| K | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| K | 0042802 | molecular_function | identical protein binding |
| L | 0003867 | molecular_function | 4-aminobutyrate transaminase activity |
| L | 0008483 | molecular_function | transaminase activity |
| L | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| L | 0030170 | molecular_function | pyridoxal phosphate binding |
| L | 0034386 | molecular_function | 4-aminobutyrate:2-oxoglutarate transaminase activity |
| L | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP A 1456 |
| Chain | Residue |
| A | SER133 |
| A | LYS295 |
| A | ABU1457 |
| A | HOH2057 |
| A | HOH2076 |
| B | THR324 |
| A | GLY134 |
| A | ALA135 |
| A | TYR161 |
| A | HIS162 |
| A | GLU233 |
| A | ASP266 |
| A | VAL268 |
| A | GLN269 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ABU A 1457 |
| Chain | Residue |
| A | TYR161 |
| A | ARG164 |
| A | GLU238 |
| A | LYS295 |
| A | PLP1456 |
| A | HOH2057 |
| B | MET102 |
| B | GLY323 |
| B | THR324 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP B 1456 |
| Chain | Residue |
| A | THR324 |
| A | HOH2042 |
| A | HOH2043 |
| B | SER133 |
| B | GLY134 |
| B | ALA135 |
| B | TYR161 |
| B | HIS162 |
| B | GLU233 |
| B | ASP266 |
| B | VAL268 |
| B | GLN269 |
| B | LYS295 |
| B | ABU1457 |
| B | HOH2077 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU B 1457 |
| Chain | Residue |
| A | MET102 |
| A | GLY323 |
| A | THR324 |
| B | TYR161 |
| B | ARG164 |
| B | GLU238 |
| B | LYS295 |
| B | PLP1456 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP C 1456 |
| Chain | Residue |
| C | SER133 |
| C | GLY134 |
| C | ALA135 |
| C | TYR161 |
| C | HIS162 |
| C | GLU233 |
| C | ASP266 |
| C | VAL268 |
| C | GLN269 |
| C | LYS295 |
| C | ABU1457 |
| C | HOH2033 |
| D | THR324 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ABU C 1457 |
| Chain | Residue |
| C | TYR161 |
| C | ARG164 |
| C | LYS295 |
| C | PLP1456 |
| D | MET102 |
| D | GLY323 |
| D | THR324 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP D 1456 |
| Chain | Residue |
| C | THR324 |
| D | SER133 |
| D | GLY134 |
| D | ALA135 |
| D | TYR161 |
| D | HIS162 |
| D | GLU233 |
| D | ASP266 |
| D | VAL268 |
| D | GLN269 |
| D | LYS295 |
| D | ABU1457 |
| D | HOH2019 |
| D | HOH2030 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU D 1457 |
| Chain | Residue |
| C | MET102 |
| D | TYR161 |
| D | ARG164 |
| D | GLU238 |
| D | LYS295 |
| D | PLP1456 |
| D | HOH2019 |
| D | HOH2021 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP E 1456 |
| Chain | Residue |
| E | HOH2064 |
| E | HOH2078 |
| E | HOH2079 |
| F | THR324 |
| E | SER133 |
| E | GLY134 |
| E | ALA135 |
| E | TYR161 |
| E | HIS162 |
| E | GLU233 |
| E | ASP266 |
| E | VAL268 |
| E | GLN269 |
| E | LYS295 |
| E | ABU1457 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ABU E 1457 |
| Chain | Residue |
| E | TYR161 |
| E | ARG164 |
| E | GLU238 |
| E | LYS295 |
| E | PLP1456 |
| F | MET102 |
| F | GLY323 |
| site_id | BC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP F 1456 |
| Chain | Residue |
| E | THR324 |
| E | HOH2035 |
| F | SER133 |
| F | GLY134 |
| F | ALA135 |
| F | TYR161 |
| F | HIS162 |
| F | GLU233 |
| F | ASP266 |
| F | VAL268 |
| F | GLN269 |
| F | LYS295 |
| F | ABU1457 |
| F | HOH2034 |
| F | HOH2036 |
| F | HOH2056 |
| F | HOH2066 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ABU F 1457 |
| Chain | Residue |
| E | GLY323 |
| E | THR324 |
| F | TYR161 |
| F | ARG164 |
| F | TYR178 |
| F | GLU238 |
| F | LYS295 |
| F | PLP1456 |
| F | HOH2034 |
| site_id | BC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP I 1457 |
| Chain | Residue |
| I | SER133 |
| I | GLY134 |
| I | ALA135 |
| I | TYR161 |
| I | HIS162 |
| I | GLU233 |
| I | ASP266 |
| I | VAL268 |
| I | GLN269 |
| I | LYS295 |
| I | ABU1458 |
| I | HOH2005 |
| L | THR324 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU I 1458 |
| Chain | Residue |
| I | TYR161 |
| I | ARG164 |
| I | GLU238 |
| I | LYS295 |
| I | PLP1457 |
| L | MET102 |
| L | GLY323 |
| L | THR324 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP J 1456 |
| Chain | Residue |
| J | SER133 |
| J | GLY134 |
| J | ALA135 |
| J | TYR161 |
| J | HIS162 |
| J | GLU233 |
| J | ASP266 |
| J | LYS295 |
| J | ABU1457 |
| K | GLY323 |
| K | THR324 |
| site_id | BC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ABU J 1457 |
| Chain | Residue |
| J | TYR161 |
| J | ARG164 |
| J | TYR178 |
| J | GLU238 |
| J | LYS295 |
| J | PLP1456 |
| K | MET102 |
| K | GLY323 |
| K | THR324 |
| site_id | BC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP K 1456 |
| Chain | Residue |
| J | THR324 |
| K | GLY134 |
| K | ALA135 |
| K | TYR161 |
| K | HIS162 |
| K | GLU233 |
| K | ASP266 |
| K | GLN269 |
| K | LYS295 |
| K | ABU1457 |
| K | HOH2004 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU K 1457 |
| Chain | Residue |
| J | MET102 |
| J | GLY323 |
| J | THR324 |
| K | TYR161 |
| K | ARG164 |
| K | GLU238 |
| K | LYS295 |
| K | PLP1456 |
| site_id | CC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP G 1456 |
| Chain | Residue |
| G | SER133 |
| G | GLY134 |
| G | ALA135 |
| G | TYR161 |
| G | HIS162 |
| G | GLU233 |
| G | ASP266 |
| G | GLN269 |
| G | LYS295 |
| G | ABU1457 |
| H | THR324 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU G 1457 |
| Chain | Residue |
| G | TYR161 |
| G | ARG164 |
| G | TYR178 |
| G | GLU238 |
| G | LYS295 |
| G | PLP1456 |
| H | MET102 |
| H | THR324 |
| site_id | CC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PLP H 1456 |
| Chain | Residue |
| G | THR324 |
| H | SER133 |
| H | GLY134 |
| H | ALA135 |
| H | TYR161 |
| H | HIS162 |
| H | GLU233 |
| H | ASP266 |
| H | VAL268 |
| H | GLN269 |
| H | LYS295 |
| H | ABU1457 |
| site_id | CC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU H 1457 |
| Chain | Residue |
| G | MET102 |
| G | GLY323 |
| G | THR324 |
| H | TYR161 |
| H | ARG164 |
| H | GLU238 |
| H | LYS295 |
| H | PLP1456 |
| site_id | CC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP L 1456 |
| Chain | Residue |
| I | THR324 |
| L | SER133 |
| L | GLY134 |
| L | ALA135 |
| L | TYR161 |
| L | HIS162 |
| L | GLU233 |
| L | ASP266 |
| L | GLN269 |
| L | LYS295 |
| L | ABU1457 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ABU L 1457 |
| Chain | Residue |
| I | MET102 |
| I | THR324 |
| L | TYR161 |
| L | ARG164 |
| L | TYR178 |
| L | GLU238 |
| L | LYS295 |
| L | PLP1456 |
Functional Information from PROSITE/UniProt
| site_id | PS00600 |
| Number of Residues | 38 |
| Details | AA_TRANSFER_CLASS_3 Aminotransferases class-III pyridoxal-phosphate attachment site. FIaDEVqs.GFcRtGewfavdhegvvp....DIItmAKgiaGG |
| Chain | Residue | Details |
| A | PHE263-GLY300 |
