4AST

The apo structure of a bacterial aldo-keto reductase AKR14A1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006974	biological_process	DNA damage response
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0051596	biological_process	methylglyoxal catabolic process
B	0006974	biological_process	DNA damage response
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0051596	biological_process	methylglyoxal catabolic process
C	0006974	biological_process	DNA damage response
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0051596	biological_process	methylglyoxal catabolic process
D	0006974	biological_process	DNA damage response
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0051596	biological_process	methylglyoxal catabolic process
E	0006974	biological_process	DNA damage response
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0051596	biological_process	methylglyoxal catabolic process
F	0006974	biological_process	DNA damage response
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0051596	biological_process	methylglyoxal catabolic process
G	0006974	biological_process	DNA damage response
G	0016491	molecular_function	oxidoreductase activity
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0051596	biological_process	methylglyoxal catabolic process
H	0006974	biological_process	DNA damage response
H	0016491	molecular_function	oxidoreductase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0051596	biological_process	methylglyoxal catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	SITE: Important for catalysis

Chain	Residue	Details
A	ASP61
C	TYR66
C	LYS97
C	HIS138
D	ASP61
D	TYR66
D	LYS97
D	HIS138
E	ASP61
E	TYR66
E	LYS97
A	TYR66
E	HIS138
F	ASP61
F	TYR66
F	LYS97
F	HIS138
G	ASP61
G	TYR66
G	LYS97
G	HIS138
H	ASP61
A	LYS97
H	TYR66
H	LYS97
H	HIS138
A	HIS138
B	ASP61
B	TYR66
B	LYS97
B	HIS138
C	ASP61

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