4ASQ

Crystal structure of ANCE in complex with Bradykinin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0008241	molecular_function	peptidyl-dipeptidase activity
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TVHHELGHIQ

Chain	Residue	Details
A	THR364-GLN373

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Cleavage; by ACE => ECO:0000269|PubMed:4322742, ECO:0000269|PubMed:6055465

Chain	Residue	Details
P	PRO7

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Cleavage; by kallikrein => ECO:0000303|PubMed:3366244

Chain	Residue	Details
P	ARG9

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: 4-hydroxyproline; partial => ECO:0000269|PubMed:3182782, ECO:0000269|PubMed:3366244

Chain	Residue	Details
P	PRO3
A	HIS371
A	GLU395

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site_id	SWS_FT_FI4
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305|PubMed:8761461

Chain	Residue	Details
A	ASN53
A	ASN196
A	ASN311

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