4ASG
The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 814 A 1215 |
| Chain | Residue |
| A | SER36 |
| A | GLY118 |
| A | GLY121 |
| A | VAL122 |
| A | GLY123 |
| A | PHE124 |
| A | THR171 |
| A | HOH2033 |
| A | HOH2038 |
| A | HOH2070 |
| A | HOH2092 |
| A | ASN37 |
| A | HOH2143 |
| A | ASP40 |
| A | ALA41 |
| A | LYS44 |
| A | ASP79 |
| A | MET84 |
| A | ASN92 |
| A | LYS98 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 1216 |
| Chain | Residue |
| A | GLU28 |
| A | HIS197 |
| A | HOH2022 |
| A | HOH2023 |
| A | HOH2135 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 1217 |
| Chain | Residue |
| A | GLU162 |
| A | GLU162 |
| A | HOH2144 |
| A | HOH2144 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 1218 |
| Chain | Residue |
| A | GLU183 |
| A | HOH2121 |
| A | HOH2125 |
| A | HOH2126 |
Functional Information from PROSITE/UniProt
| site_id | PS00298 |
| Number of Residues | 10 |
| Details | HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE |
| Chain | Residue | Details |
| A | TYR24-GLU33 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16625188","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CG9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16625188","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9230303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AM1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WEP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
