4AQR

Crystal structure of calmodulin in complex with the regulatory domain of a plasma-membrane Ca2+-ATPase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005513	biological_process	detection of calcium ion
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0010099	biological_process	regulation of photomorphogenesis
A	0030234	molecular_function	enzyme regulator activity
A	0050832	biological_process	defense response to fungus
B	0005509	molecular_function	calcium ion binding
B	0005513	biological_process	detection of calcium ion
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0010099	biological_process	regulation of photomorphogenesis
B	0030234	molecular_function	enzyme regulator activity
B	0050832	biological_process	defense response to fungus
D	0005516	molecular_function	calmodulin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 150

Chain	Residue
A	ASP21
A	ASP23
A	ASP25
A	CYS27
A	GLU32
A	HOH2017

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 151

Chain	Residue
A	THR63
A	GLU68
A	HOH2050
A	ASP57
A	ASP59
A	ASN61

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 152

Chain	Residue
A	ASP94
A	ASP96
A	ASN98
A	PHE100
A	GLU105
A	HOH2064

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 153

Chain	Residue
A	ASP130
A	ASP132
A	ASP134
A	GLN136
A	GLU141
A	HOH2087

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 150

Chain	Residue
B	ASP21
B	ASP23
B	ASP25
B	CYS27
B	GLU32
B	HOH2020

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA B 151

Chain	Residue
B	ASP57
B	ASP59
B	ASN61
B	THR63
B	GLU68
B	HOH2050
B	HOH2051

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 152

Chain	Residue
B	ASP130
B	ASP132
B	ASP134
B	GLN136
B	GLU141
B	HOH2076

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 153

Chain	Residue
B	ASP94
B	ASP96
B	ASN98
B	PHE100
B	GLU105
B	HOH2063

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGCITtkEL

Chain	Residue	Details
A	ASP21-LEU33
A	ASP57-PHE69
A	ASP94-LEU106
A	ASP130-PHE142

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	70
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	38
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	11
Details	Region: {"description":"Interaction with calmodulin"}

Chain

Residue

Details

---