4AQ0

Structure of the Gh92 Family Glycosyl Hydrolase Ccman5 in complex with deoxymannojirimycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000224	molecular_function	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
A	0004559	molecular_function	alpha-mannosidase activity
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
A	0006516	biological_process	glycoprotein catabolic process
A	0006517	biological_process	protein deglycosylation
A	0030246	molecular_function	carbohydrate binding
A	0046872	molecular_function	metal ion binding
B	0000224	molecular_function	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
B	0004559	molecular_function	alpha-mannosidase activity
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
B	0006516	biological_process	glycoprotein catabolic process
B	0006517	biological_process	protein deglycosylation
B	0030246	molecular_function	carbohydrate binding
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 1772

Chain	Residue
A	ASN588
A	GLU589
A	ASP662
A	HOH2418

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE B3P A 1773

Chain	Residue
A	ARG405
A	HOH2273
A	HOH2274
A	HOH2514
A	VAL70
A	GLY71
A	GLY72
A	ASP355
A	VAL404

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1772

Chain	Residue
B	ASN588
B	GLU589
B	ASP662
B	DMJ1773
B	HOH2439
B	HOH2440

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site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DMJ B 1773

Chain	Residue
B	VAL70
B	GLY71
B	TYR196
B	TRP354
B	ASP355
B	ARG405
B	TYR535
B	GLN536
B	GLU589
B	ASP662
B	CA1772
B	HOH2057
B	HOH2059
B	HOH2302
B	HOH2408
B	HOH2440

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