4AOO
B. subtilis dUTPase YncF in complex with dU PPi and Mg in H32
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004170 | molecular_function | dUTP diphosphatase activity |
| A | 0006226 | biological_process | dUMP biosynthetic process |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046081 | biological_process | dUTP catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004170 | molecular_function | dUTP diphosphatase activity |
| B | 0006226 | biological_process | dUMP biosynthetic process |
| B | 0009117 | biological_process | nucleotide metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046081 | biological_process | dUTP catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004170 | molecular_function | dUTP diphosphatase activity |
| C | 0006226 | biological_process | dUMP biosynthetic process |
| C | 0009117 | biological_process | nucleotide metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046081 | biological_process | dUTP catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004170 | molecular_function | dUTP diphosphatase activity |
| D | 0006226 | biological_process | dUMP biosynthetic process |
| D | 0009117 | biological_process | nucleotide metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046081 | biological_process | dUTP catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE DUR A 1145 |
| Chain | Residue |
| A | SER64 |
| A | ARG135 |
| A | GLY137 |
| A | POP1146 |
| A | HOH2036 |
| A | ASN76 |
| A | GLY79 |
| A | VAL80 |
| A | ASP82 |
| A | TYR85 |
| A | TRP92 |
| A | PHE93 |
| A | PRO95 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DUR B 1145 |
| Chain | Residue |
| B | ASN76 |
| B | GLY79 |
| B | VAL80 |
| B | ILE81 |
| B | ASP82 |
| B | TYR85 |
| B | TRP92 |
| B | PHE93 |
| B | PRO95 |
| B | HOH2047 |
| C | ARG135 |
| C | GLY137 |
| C | LEU138 |
| C | POP1147 |
| D | SER64 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE DUR C 1145 |
| Chain | Residue |
| B | SER64 |
| B | HOH2056 |
| C | ASN76 |
| C | GLY79 |
| C | VAL80 |
| C | ILE81 |
| C | ASP82 |
| C | TYR85 |
| C | TRP92 |
| C | PHE93 |
| C | PRO95 |
| C | HOH2037 |
| D | POP1146 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE DUR D 1145 |
| Chain | Residue |
| B | ARG135 |
| B | GLY137 |
| B | POP1146 |
| B | HOH2075 |
| C | SER64 |
| D | ASN76 |
| D | GLY79 |
| D | VAL80 |
| D | ILE81 |
| D | ASP82 |
| D | TYR85 |
| D | TRP92 |
| D | PHE93 |
| D | PRO95 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 C 1146 |
| Chain | Residue |
| B | GLN74 |
| B | SER77 |
| C | GLN74 |
| C | SER77 |
| D | GLN74 |
| D | SER77 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1148 |
| Chain | Residue |
| A | POP1146 |
| A | HOH2038 |
| A | HOH2052 |
| A | HOH2053 |
| A | HOH2054 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1148 |
| Chain | Residue |
| B | POP1146 |
| B | HOH2069 |
| B | HOH2070 |
| B | HOH2072 |
| B | HOH2074 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 1148 |
| Chain | Residue |
| B | HOH2049 |
| C | POP1147 |
| C | HOH2051 |
| C | HOH2053 |
| C | HOH2054 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 1148 |
| Chain | Residue |
| B | HOH2022 |
| B | HOH2023 |
| C | HOH2037 |
| D | POP1146 |
| D | HOH2042 |
| site_id | BC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE POP A 1146 |
| Chain | Residue |
| A | ARG63 |
| A | SER64 |
| A | SER65 |
| A | ARG135 |
| A | GLY137 |
| A | GLY139 |
| A | SER140 |
| A | THR141 |
| A | DUR1145 |
| A | MG1148 |
| A | HOH2038 |
| A | HOH2052 |
| A | HOH2054 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE POP B 1146 |
| Chain | Residue |
| B | MG1148 |
| B | HOH2069 |
| B | HOH2070 |
| B | HOH2072 |
| B | HOH2074 |
| C | ARG63 |
| C | SER64 |
| C | SER65 |
| D | DUR1145 |
| B | ARG135 |
| B | GLY137 |
| B | GLY139 |
| B | SER140 |
| B | THR141 |
| site_id | BC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE POP D 1146 |
| Chain | Residue |
| B | ARG63 |
| B | SER64 |
| B | SER65 |
| B | HOH2022 |
| B | HOH2023 |
| C | DUR1145 |
| C | HOH2037 |
| D | ARG135 |
| D | GLY137 |
| D | GLY139 |
| D | SER140 |
| D | THR141 |
| D | MG1148 |
| site_id | BC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE POP C 1147 |
| Chain | Residue |
| B | DUR1145 |
| B | HOH2049 |
| C | ARG135 |
| C | GLY137 |
| C | GLY139 |
| C | SER140 |
| C | THR141 |
| C | MG1148 |
| C | HOH2051 |
| C | HOH2053 |
| C | HOH2054 |
| D | ARG63 |
| D | SER64 |
| D | SER65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:20823546, ECO:0000305|PubMed:23897460 |
| Chain | Residue | Details |
| A | ASP82 | |
| B | ASP82 | |
| C | ASP82 | |
| D | ASP82 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:20823546, ECO:0007744|PDB:2XCE |
| Chain | Residue | Details |
| A | SER64 | |
| C | ASN76 | |
| C | TYR85 | |
| C | PHE93 | |
| D | SER64 | |
| D | ASN76 | |
| D | TYR85 | |
| D | PHE93 | |
| A | ASN76 | |
| A | TYR85 | |
| A | PHE93 | |
| B | SER64 | |
| B | ASN76 | |
| B | TYR85 | |
| B | PHE93 | |
| C | SER64 |
