Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4AO5

B. subtilis prophage dUTPase YosS in complex with dUMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004170	molecular_function	dUTP diphosphatase activity
A	0006226	biological_process	dUMP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0046081	biological_process	dUTP catabolic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004170	molecular_function	dUTP diphosphatase activity
B	0006226	biological_process	dUMP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0046081	biological_process	dUTP catabolic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004170	molecular_function	dUTP diphosphatase activity
C	0006226	biological_process	dUMP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0046081	biological_process	dUTP catabolic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004170	molecular_function	dUTP diphosphatase activity
D	0006226	biological_process	dUMP biosynthetic process
D	0009117	biological_process	nucleotide metabolic process
D	0016787	molecular_function	hydrolase activity
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0046081	biological_process	dUTP catabolic process
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004170	molecular_function	dUTP diphosphatase activity
E	0006226	biological_process	dUMP biosynthetic process
E	0009117	biological_process	nucleotide metabolic process
E	0016787	molecular_function	hydrolase activity
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
E	0046081	biological_process	dUTP catabolic process
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0004170	molecular_function	dUTP diphosphatase activity
F	0006226	biological_process	dUMP biosynthetic process
F	0009117	biological_process	nucleotide metabolic process
F	0016787	molecular_function	hydrolase activity
F	0032991	cellular_component	protein-containing complex
F	0042802	molecular_function	identical protein binding
F	0046081	biological_process	dUTP catabolic process
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE UMP A 1129

Chain	Residue
A	ASN74
A	HOH2207
A	HOH2208
A	HOH2210
C	SER62
D	LYS103
A	GLY77
A	ILE79
A	TYR83
A	TRP90
A	PHE91
A	PRO93
A	HOH2145
A	HOH2206

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 1130

Chain	Residue
A	ASN16
A	ILE24
A	ASP25
A	ARG27
A	HOH2042

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE UMP B 1129

Chain	Residue
A	SER62
A	HOH2120
A	HOH2127
A	HOH2128
B	ASN74
B	GLY77
B	ILE79
B	TYR83
B	TRP90
B	PHE91
B	PRO93
B	HOH2150
B	HOH2205
B	HOH2206
B	HOH2207
E	LYS101
E	LYS103

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA B 1130

Chain	Residue
B	THR13
B	GLY105
F	ARG107

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE UMP C 1129

Chain	Residue
B	SER62
B	SER63
B	HOH2129
B	HOH2135
B	HOH2137
C	ASN74
C	GLY77
C	TYR83
C	TRP90
C	PHE91
C	PRO93
C	HOH2154
C	HOH2155
C	HOH2156
C	HOH2157
C	HOH2158

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 1130

Chain	Residue
C	ARG107
D	THR13
D	GLY105

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE UMP D 1129

Chain	Residue
B	LYS103
B	HOH2180
D	ASN74
D	GLY77
D	ILE79
D	TYR83
D	TRP90
D	PHE91
D	PRO93
D	HOH2159
D	HOH2220
D	HOH2221
D	HOH2222
D	HOH2223
D	HOH2224
D	HOH2226
F	SER62

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA D 1130

Chain	Residue
D	ARG14
D	ILE15
D	ASN16
D	ARG27
D	HOH2042

site_id	AC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE UMP E 1129

Chain	Residue
D	SER62
D	SER63
D	HOH2133
D	HOH2139
D	HOH2142
E	ASN74
E	GLY77
E	ILE79
E	TYR83
E	TRP90
E	PHE91
E	PRO93
E	HOH2184
E	HOH2185
E	HOH2186
E	HOH2187
E	HOH2188

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA E 1130

Chain	Residue
E	GLY105
A	ARG107
E	THR13

site_id	BC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE UMP F 1129

Chain	Residue
E	SER62
E	HOH2112
E	HOH2116
E	HOH2121
F	ASN74
F	GLY77
F	ILE79
F	TYR83
F	TRP90
F	PHE91
F	PRO93
F	HOH2148
F	HOH2149
F	HOH2150
F	HOH2151
F	HOH2153

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton acceptor => ECO:0000305\|PubMed:21358047, ECO:0000305\|PubMed:23897460

Chain	Residue	Details
A	ASP80
B	ASP80
C	ASP80
D	ASP80
E	ASP80
F	ASP80

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:23897460, ECO:0007744\|PDB:4AO5

Chain	Residue	Details
A	SER62
C	ASN74
C	TYR83
C	PHE91
D	SER62
D	ASN74
D	TYR83
D	PHE91
E	SER62
E	ASN74
E	TYR83
A	ASN74
E	PHE91
F	SER62
F	ASN74
F	TYR83
F	PHE91
A	TYR83
A	PHE91
B	SER62
B	ASN74
B	TYR83
B	PHE91
C	SER62

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)