Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE PLK A 1446 |
| Chain | Residue |
| A | ARG54 |
| A | GLY174 |
| A | GLU220 |
| A | ALA225 |
| A | ASP253 |
| A | VAL255 |
| A | MET256 |
| A | LYS280 |
| A | HOH2115 |
| A | HOH2116 |
| A | HOH2118 |
| A | ILE56 |
| A | HOH2149 |
| A | HOH2231 |
| B | ALA312 |
| B | GLY313 |
| B | THR314 |
| A | TYR89 |
| A | SER144 |
| A | GLY145 |
| A | THR146 |
| A | ASN149 |
| A | TYR172 |
| A | HIS173 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1447 |
| Chain | Residue |
| A | GLY170 |
| A | ALA180 |
| A | GLY226 |
| A | ALA384 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1448 |
| Chain | Residue |
| A | LEU124 |
| A | GLU127 |
| A | HIS326 |
| A | HOH2103 |
| C | ARG43 |
| C | GLU120 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE PLK B 1445 |
| Chain | Residue |
| A | ALA312 |
| A | GLY313 |
| A | THR314 |
| A | HOH2113 |
| A | HOH2114 |
| A | HOH2182 |
| B | ARG54 |
| B | ILE56 |
| B | TYR89 |
| B | SER144 |
| B | GLY145 |
| B | THR146 |
| B | ASN149 |
| B | TYR172 |
| B | HIS173 |
| B | GLY174 |
| B | GLU220 |
| B | ALA225 |
| B | ASP253 |
| B | VAL255 |
| B | MET256 |
| B | LYS280 |
| B | HOH2069 |
| B | HOH2100 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1446 |
| Chain | Residue |
| B | PRO221 |
| B | ALA231 |
| B | HOH2180 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1447 |
| Chain | Residue |
| B | ALA180 |
| B | GLY226 |
| B | ALA384 |
| B | HOH2084 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1448 |
| Chain | Residue |
| B | ASP33 |
| B | ASN34 |
| B | TYR82 |
| B | EDO1449 |
| B | HOH2170 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1449 |
| Chain | Residue |
| B | ALA81 |
| B | LEU403 |
| B | GLY406 |
| B | EDO1448 |
| site_id | AC9 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE PLK C 1445 |
| Chain | Residue |
| C | ARG54 |
| C | ILE56 |
| C | TYR89 |
| C | SER144 |
| C | GLY145 |
| C | THR146 |
| C | ASN149 |
| C | TYR172 |
| C | HIS173 |
| C | GLY174 |
| C | GLU220 |
| C | ALA225 |
| C | ASP253 |
| C | VAL255 |
| C | MET256 |
| C | LYS280 |
| C | ALA312 |
| C | GLY313 |
| C | THR314 |
| C | HOH2087 |
| C | HOH2088 |
| C | HOH2089 |
| C | HOH2090 |
| C | HOH2121 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1446 |
| Chain | Residue |
| A | HOH2091 |
| B | ARG43 |
| C | GLU127 |
| C | ALA128 |
| C | HIS326 |
| C | HOH2072 |
| A | GLU120 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1447 |
| Chain | Residue |
| C | ASP33 |
| C | ASN34 |
| C | TYR82 |
| C | ARG404 |
| C | HOH2198 |
