4AND

CRYSTAL FORM II OF THE D93N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001907	biological_process	symbiont-mediated killing of host cell
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004844	molecular_function	uracil DNA N-glycosylase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006163	biological_process	purine nucleotide metabolic process
A	0006183	biological_process	GTP biosynthetic process
A	0006220	biological_process	pyrimidine nucleotide metabolic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
A	0141127	biological_process	symbiont-mediated perturbation of host Rab small GTPase signal transduction
B	0000166	molecular_function	nucleotide binding
B	0001907	biological_process	symbiont-mediated killing of host cell
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0004844	molecular_function	uracil DNA N-glycosylase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006163	biological_process	purine nucleotide metabolic process
B	0006183	biological_process	GTP biosynthetic process
B	0006220	biological_process	pyrimidine nucleotide metabolic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0046872	molecular_function	metal ion binding
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0141127	biological_process	symbiont-mediated perturbation of host Rab small GTPase signal transduction

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	HIS117
B	HIS117

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	LYS10
B	THR92
B	ARG104
B	ASN114
A	PHE58
A	ARG86
A	THR92
A	ARG104
A	ASN114
B	LYS10
B	PHE58
B	ARG86

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