Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004360 | molecular_function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| A | 0006047 | biological_process | UDP-N-acetylglucosamine metabolic process |
| A | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
| A | 0006487 | biological_process | protein N-linked glycosylation |
| A | 0006541 | biological_process | glutamine metabolic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0097367 | molecular_function | carbohydrate derivative binding |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
| A | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
| B | 0004360 | molecular_function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| B | 0006047 | biological_process | UDP-N-acetylglucosamine metabolic process |
| B | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
| B | 0006487 | biological_process | protein N-linked glycosylation |
| B | 0006541 | biological_process | glutamine metabolic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0097367 | molecular_function | carbohydrate derivative binding |
| B | 1901135 | biological_process | carbohydrate derivative metabolic process |
| B | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
| C | 0004360 | molecular_function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| C | 0006047 | biological_process | UDP-N-acetylglucosamine metabolic process |
| C | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
| C | 0006487 | biological_process | protein N-linked glycosylation |
| C | 0006541 | biological_process | glutamine metabolic process |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0097367 | molecular_function | carbohydrate derivative binding |
| C | 1901135 | biological_process | carbohydrate derivative metabolic process |
| C | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE F6R A 1609 |
| Chain | Residue |
| A | CYS300 |
| A | ALA400 |
| A | SER401 |
| A | LYS485 |
| A | GLU488 |
| A | HIS504 |
| A | HOH2228 |
| A | HOH2233 |
| A | HOH2274 |
| A | HOH2278 |
| A | HOH2307 |
| A | GLY301 |
| A | HOH2308 |
| A | HOH2427 |
| A | THR302 |
| A | SER303 |
| A | SER347 |
| A | GLN348 |
| A | SER349 |
| A | THR352 |
| A | VAL399 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE F6R C 1609 |
| Chain | Residue |
| B | HIS504 |
| C | CYS300 |
| C | GLY301 |
| C | THR302 |
| C | SER303 |
| C | SER347 |
| C | GLN348 |
| C | SER349 |
| C | THR352 |
| C | ALA400 |
| C | SER401 |
| C | LYS485 |
| C | GLU488 |
| C | HOH2171 |
| C | HOH2180 |
| C | HOH2183 |
| C | HOH2207 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE F6R B 1609 |
| Chain | Residue |
| B | CYS300 |
| B | GLY301 |
| B | THR302 |
| B | SER303 |
| B | SER347 |
| B | GLN348 |
| B | SER349 |
| B | THR352 |
| B | VAL399 |
| B | ALA400 |
| B | SER401 |
| B | LYS485 |
| B | GLU488 |
| B | HOH2014 |
| B | HOH2018 |
| C | HIS504 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Nucleophile; for GATase activity => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS1 | |
| B | CYS1 | |
| C | CYS1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | ACT_SITE: For Fru-6P isomerization activity |
| Chain | Residue | Details |
| A | LYS603 | |
| B | LYS603 | |
| C | LYS603 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 10 |
| Details | M-CSA 82 |
| Chain | Residue | Details |
| A | CYS1 | covalently attached, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | LYS603 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ARG26 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| A | TRP74 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN98 | electrostatic stabiliser, hydrogen bond donor |
| A | GLY99 | electrostatic stabiliser, hydrogen bond donor |
| A | GLU481 | electrostatic stabiliser, hydrogen bond acceptor |
| A | LYS485 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLU488 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS504 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 10 |
| Details | M-CSA 82 |
| Chain | Residue | Details |
| B | CYS1 | covalently attached, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | LYS603 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | ARG26 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| B | TRP74 | electrostatic stabiliser, hydrogen bond donor |
| B | ASN98 | electrostatic stabiliser, hydrogen bond donor |
| B | GLY99 | electrostatic stabiliser, hydrogen bond donor |
| B | GLU481 | electrostatic stabiliser, hydrogen bond acceptor |
| B | LYS485 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | GLU488 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | HIS504 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 10 |
| Details | M-CSA 82 |
| Chain | Residue | Details |
| C | CYS1 | covalently attached, nucleofuge, nucleophile, proton acceptor, proton donor |
| C | LYS603 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| C | ARG26 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| C | TRP74 | electrostatic stabiliser, hydrogen bond donor |
| C | ASN98 | electrostatic stabiliser, hydrogen bond donor |
| C | GLY99 | electrostatic stabiliser, hydrogen bond donor |
| C | GLU481 | electrostatic stabiliser, hydrogen bond acceptor |
| C | LYS485 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | GLU488 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | HIS504 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
