Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| D | 0007165 | biological_process | signal transduction |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D 1770 |
| Chain | Residue |
| D | HIS529 |
| D | HIS563 |
| D | ASP564 |
| D | ASP674 |
| D | HOH2019 |
| D | HOH2024 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1769 |
| Chain | Residue |
| A | ASP674 |
| A | HOH2019 |
| A | HIS529 |
| A | HIS563 |
| A | ASP564 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 1771 |
| Chain | Residue |
| D | ASP564 |
| D | HOH2020 |
| D | HOH2023 |
| D | HOH2024 |
| D | HOH2025 |
| D | HOH2028 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1770 |
| Chain | Residue |
| A | ASP564 |
| A | HOH2018 |
| A | HOH2019 |
| A | HOH2020 |
| A | HOH2022 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE F07 A 1771 |
| Chain | Residue |
| A | VAL678 |
| A | ILE692 |
| A | MET713 |
| A | GLN726 |
| A | PHE729 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE F07 D 1772 |
| Chain | Residue |
| D | SER677 |
| D | ILE692 |
| D | MET713 |
| D | GLN726 |
| D | PHE729 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS563-TYR574 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 317 |
| Details | Domain: {"description":"PDEase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01192","evidenceCode":"ECO:0000255"}]} |
