4AJ5

Crystal structure of the Ska core complex

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000940	cellular_component	outer kinetochore
1	0007059	biological_process	chromosome segregation
2	0000940	cellular_component	outer kinetochore
2	0007059	biological_process	chromosome segregation
3	0000940	cellular_component	outer kinetochore
3	0007059	biological_process	chromosome segregation
4	0000940	cellular_component	outer kinetochore
4	0007059	biological_process	chromosome segregation
A	0007059	biological_process	chromosome segregation
A	0008017	molecular_function	microtubule binding
A	0051301	biological_process	cell division
B	0007059	biological_process	chromosome segregation
B	0008017	molecular_function	microtubule binding
B	0051301	biological_process	cell division
C	0007059	biological_process	chromosome segregation
C	0008017	molecular_function	microtubule binding
C	0051301	biological_process	cell division
D	0007059	biological_process	chromosome segregation
D	0008017	molecular_function	microtubule binding
D	0051301	biological_process	cell division
E	0007059	biological_process	chromosome segregation
E	0008017	molecular_function	microtubule binding
E	0051301	biological_process	cell division
F	0007059	biological_process	chromosome segregation
F	0008017	molecular_function	microtubule binding
F	0051301	biological_process	cell division
G	0007059	biological_process	chromosome segregation
G	0008017	molecular_function	microtubule binding
G	0051301	biological_process	cell division
H	0007059	biological_process	chromosome segregation
H	0008017	molecular_function	microtubule binding
H	0051301	biological_process	cell division
I	0007059	biological_process	chromosome segregation
I	0008017	molecular_function	microtubule binding
I	0051301	biological_process	cell division
J	0007059	biological_process	chromosome segregation
J	0008017	molecular_function	microtubule binding
J	0051301	biological_process	cell division
K	0000070	biological_process	mitotic sister chromatid segregation
K	0000278	biological_process	mitotic cell cycle
K	0000775	cellular_component	chromosome, centromeric region
K	0000776	cellular_component	kinetochore
K	0000940	cellular_component	outer kinetochore
K	0005515	molecular_function	protein binding
K	0005694	cellular_component	chromosome
K	0005737	cellular_component	cytoplasm
K	0005819	cellular_component	spindle
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0005874	cellular_component	microtubule
K	0005876	cellular_component	spindle microtubule
K	0007056	biological_process	spindle assembly involved in female meiosis
K	0007059	biological_process	chromosome segregation
K	0007080	biological_process	mitotic metaphase chromosome alignment
K	0008017	molecular_function	microtubule binding
K	0031110	biological_process	regulation of microtubule polymerization or depolymerization
K	0051296	biological_process	establishment of meiotic spindle orientation
K	0051301	biological_process	cell division
K	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
K	0072687	cellular_component	meiotic spindle
K	0170027	cellular_component	SKA complex
L	0000070	biological_process	mitotic sister chromatid segregation
L	0000278	biological_process	mitotic cell cycle
L	0000775	cellular_component	chromosome, centromeric region
L	0000776	cellular_component	kinetochore
L	0000940	cellular_component	outer kinetochore
L	0005515	molecular_function	protein binding
L	0005694	cellular_component	chromosome
L	0005737	cellular_component	cytoplasm
L	0005819	cellular_component	spindle
L	0005829	cellular_component	cytosol
L	0005856	cellular_component	cytoskeleton
L	0005874	cellular_component	microtubule
L	0005876	cellular_component	spindle microtubule
L	0007056	biological_process	spindle assembly involved in female meiosis
L	0007059	biological_process	chromosome segregation
L	0007080	biological_process	mitotic metaphase chromosome alignment
L	0008017	molecular_function	microtubule binding
L	0031110	biological_process	regulation of microtubule polymerization or depolymerization
L	0051296	biological_process	establishment of meiotic spindle orientation
L	0051301	biological_process	cell division
L	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
L	0072687	cellular_component	meiotic spindle
L	0170027	cellular_component	SKA complex
M	0000070	biological_process	mitotic sister chromatid segregation
M	0000278	biological_process	mitotic cell cycle
M	0000775	cellular_component	chromosome, centromeric region
M	0000776	cellular_component	kinetochore
M	0000940	cellular_component	outer kinetochore
M	0005515	molecular_function	protein binding
M	0005694	cellular_component	chromosome
M	0005737	cellular_component	cytoplasm
M	0005819	cellular_component	spindle
M	0005829	cellular_component	cytosol
M	0005856	cellular_component	cytoskeleton
M	0005874	cellular_component	microtubule
M	0005876	cellular_component	spindle microtubule
M	0007056	biological_process	spindle assembly involved in female meiosis
M	0007059	biological_process	chromosome segregation
M	0007080	biological_process	mitotic metaphase chromosome alignment
M	0008017	molecular_function	microtubule binding
M	0031110	biological_process	regulation of microtubule polymerization or depolymerization
M	0051296	biological_process	establishment of meiotic spindle orientation
M	0051301	biological_process	cell division
M	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
M	0072687	cellular_component	meiotic spindle
M	0170027	cellular_component	SKA complex
N	0000070	biological_process	mitotic sister chromatid segregation
N	0000278	biological_process	mitotic cell cycle
N	0000775	cellular_component	chromosome, centromeric region
N	0000776	cellular_component	kinetochore
N	0000940	cellular_component	outer kinetochore
N	0005515	molecular_function	protein binding
N	0005694	cellular_component	chromosome
N	0005737	cellular_component	cytoplasm
N	0005819	cellular_component	spindle
N	0005829	cellular_component	cytosol
N	0005856	cellular_component	cytoskeleton
N	0005874	cellular_component	microtubule
N	0005876	cellular_component	spindle microtubule
N	0007056	biological_process	spindle assembly involved in female meiosis
N	0007059	biological_process	chromosome segregation
N	0007080	biological_process	mitotic metaphase chromosome alignment
N	0008017	molecular_function	microtubule binding
N	0031110	biological_process	regulation of microtubule polymerization or depolymerization
N	0051296	biological_process	establishment of meiotic spindle orientation
N	0051301	biological_process	cell division
N	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
N	0072687	cellular_component	meiotic spindle
N	0170027	cellular_component	SKA complex
O	0000070	biological_process	mitotic sister chromatid segregation
O	0000278	biological_process	mitotic cell cycle
O	0000775	cellular_component	chromosome, centromeric region
O	0000776	cellular_component	kinetochore
O	0000940	cellular_component	outer kinetochore
O	0005515	molecular_function	protein binding
O	0005694	cellular_component	chromosome
O	0005737	cellular_component	cytoplasm
O	0005819	cellular_component	spindle
O	0005829	cellular_component	cytosol
O	0005856	cellular_component	cytoskeleton
O	0005874	cellular_component	microtubule
O	0005876	cellular_component	spindle microtubule
O	0007056	biological_process	spindle assembly involved in female meiosis
O	0007059	biological_process	chromosome segregation
O	0007080	biological_process	mitotic metaphase chromosome alignment
O	0008017	molecular_function	microtubule binding
O	0031110	biological_process	regulation of microtubule polymerization or depolymerization
O	0051296	biological_process	establishment of meiotic spindle orientation
O	0051301	biological_process	cell division
O	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
O	0072687	cellular_component	meiotic spindle
O	0170027	cellular_component	SKA complex
P	0000070	biological_process	mitotic sister chromatid segregation
P	0000278	biological_process	mitotic cell cycle
P	0000775	cellular_component	chromosome, centromeric region
P	0000776	cellular_component	kinetochore
P	0000940	cellular_component	outer kinetochore
P	0005515	molecular_function	protein binding
P	0005694	cellular_component	chromosome
P	0005737	cellular_component	cytoplasm
P	0005819	cellular_component	spindle
P	0005829	cellular_component	cytosol
P	0005856	cellular_component	cytoskeleton
P	0005874	cellular_component	microtubule
P	0005876	cellular_component	spindle microtubule
P	0007056	biological_process	spindle assembly involved in female meiosis
P	0007059	biological_process	chromosome segregation
P	0007080	biological_process	mitotic metaphase chromosome alignment
P	0008017	molecular_function	microtubule binding
P	0031110	biological_process	regulation of microtubule polymerization or depolymerization
P	0051296	biological_process	establishment of meiotic spindle orientation
P	0051301	biological_process	cell division
P	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
P	0072687	cellular_component	meiotic spindle
P	0170027	cellular_component	SKA complex
Q	0000070	biological_process	mitotic sister chromatid segregation
Q	0000278	biological_process	mitotic cell cycle
Q	0000775	cellular_component	chromosome, centromeric region
Q	0000776	cellular_component	kinetochore
Q	0000940	cellular_component	outer kinetochore
Q	0005515	molecular_function	protein binding
Q	0005694	cellular_component	chromosome
Q	0005737	cellular_component	cytoplasm
Q	0005819	cellular_component	spindle
Q	0005829	cellular_component	cytosol
Q	0005856	cellular_component	cytoskeleton
Q	0005874	cellular_component	microtubule
Q	0005876	cellular_component	spindle microtubule
Q	0007056	biological_process	spindle assembly involved in female meiosis
Q	0007059	biological_process	chromosome segregation
Q	0007080	biological_process	mitotic metaphase chromosome alignment
Q	0008017	molecular_function	microtubule binding
Q	0031110	biological_process	regulation of microtubule polymerization or depolymerization
Q	0051296	biological_process	establishment of meiotic spindle orientation
Q	0051301	biological_process	cell division
Q	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
Q	0072687	cellular_component	meiotic spindle
Q	0170027	cellular_component	SKA complex
R	0000070	biological_process	mitotic sister chromatid segregation
R	0000278	biological_process	mitotic cell cycle
R	0000775	cellular_component	chromosome, centromeric region
R	0000776	cellular_component	kinetochore
R	0000940	cellular_component	outer kinetochore
R	0005515	molecular_function	protein binding
R	0005694	cellular_component	chromosome
R	0005737	cellular_component	cytoplasm
R	0005819	cellular_component	spindle
R	0005829	cellular_component	cytosol
R	0005856	cellular_component	cytoskeleton
R	0005874	cellular_component	microtubule
R	0005876	cellular_component	spindle microtubule
R	0007056	biological_process	spindle assembly involved in female meiosis
R	0007059	biological_process	chromosome segregation
R	0007080	biological_process	mitotic metaphase chromosome alignment
R	0008017	molecular_function	microtubule binding
R	0031110	biological_process	regulation of microtubule polymerization or depolymerization
R	0051296	biological_process	establishment of meiotic spindle orientation
R	0051301	biological_process	cell division
R	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
R	0072687	cellular_component	meiotic spindle
R	0170027	cellular_component	SKA complex
S	0000070	biological_process	mitotic sister chromatid segregation
S	0000278	biological_process	mitotic cell cycle
S	0000775	cellular_component	chromosome, centromeric region
S	0000776	cellular_component	kinetochore
S	0000940	cellular_component	outer kinetochore
S	0005515	molecular_function	protein binding
S	0005694	cellular_component	chromosome
S	0005737	cellular_component	cytoplasm
S	0005819	cellular_component	spindle
S	0005829	cellular_component	cytosol
S	0005856	cellular_component	cytoskeleton
S	0005874	cellular_component	microtubule
S	0005876	cellular_component	spindle microtubule
S	0007056	biological_process	spindle assembly involved in female meiosis
S	0007059	biological_process	chromosome segregation
S	0007080	biological_process	mitotic metaphase chromosome alignment
S	0008017	molecular_function	microtubule binding
S	0031110	biological_process	regulation of microtubule polymerization or depolymerization
S	0051296	biological_process	establishment of meiotic spindle orientation
S	0051301	biological_process	cell division
S	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
S	0072687	cellular_component	meiotic spindle
S	0170027	cellular_component	SKA complex
T	0000070	biological_process	mitotic sister chromatid segregation
T	0000278	biological_process	mitotic cell cycle
T	0000775	cellular_component	chromosome, centromeric region
T	0000776	cellular_component	kinetochore
T	0000940	cellular_component	outer kinetochore
T	0005515	molecular_function	protein binding
T	0005694	cellular_component	chromosome
T	0005737	cellular_component	cytoplasm
T	0005819	cellular_component	spindle
T	0005829	cellular_component	cytosol
T	0005856	cellular_component	cytoskeleton
T	0005874	cellular_component	microtubule
T	0005876	cellular_component	spindle microtubule
T	0007056	biological_process	spindle assembly involved in female meiosis
T	0007059	biological_process	chromosome segregation
T	0007080	biological_process	mitotic metaphase chromosome alignment
T	0008017	molecular_function	microtubule binding
T	0031110	biological_process	regulation of microtubule polymerization or depolymerization
T	0051296	biological_process	establishment of meiotic spindle orientation
T	0051301	biological_process	cell division
T	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
T	0072687	cellular_component	meiotic spindle
T	0170027	cellular_component	SKA complex
U	0000940	cellular_component	outer kinetochore
U	0007059	biological_process	chromosome segregation
V	0000940	cellular_component	outer kinetochore
V	0007059	biological_process	chromosome segregation
W	0000940	cellular_component	outer kinetochore
W	0007059	biological_process	chromosome segregation
X	0000940	cellular_component	outer kinetochore
X	0007059	biological_process	chromosome segregation
Y	0000940	cellular_component	outer kinetochore
Y	0007059	biological_process	chromosome segregation
Z	0000940	cellular_component	outer kinetochore
Z	0007059	biological_process	chromosome segregation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:23186163

Chain	Residue	Details
K	SER101
T	LEU100
L	LEU100
M	GLU99
N	SER101
O	LEU100
P	LEU100
Q	LEU100
R	LEU100
S	GLU99

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