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4AH6

Human mitochondrial aspartyl-tRNA synthetase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000049molecular_functiontRNA binding
A0000166molecular_functionnucleotide binding
A0003676molecular_functionnucleic acid binding
A0004812molecular_functionaminoacyl-tRNA ligase activity
A0004815molecular_functionaspartate-tRNA ligase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005759cellular_componentmitochondrial matrix
A0006412biological_processtranslation
A0006418biological_processtRNA aminoacylation for protein translation
A0006422biological_processaspartyl-tRNA aminoacylation
A0016020cellular_componentmembrane
A0016874molecular_functionligase activity
A0031966cellular_componentmitochondrial membrane
A0042803molecular_functionprotein homodimerization activity
A0043039biological_processtRNA aminoacylation
A0050560molecular_functionaspartate-tRNA(Asn) ligase activity
A0070145biological_processmitochondrial asparaginyl-tRNA aminoacylation
B0000049molecular_functiontRNA binding
B0000166molecular_functionnucleotide binding
B0003676molecular_functionnucleic acid binding
B0004812molecular_functionaminoacyl-tRNA ligase activity
B0004815molecular_functionaspartate-tRNA ligase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005759cellular_componentmitochondrial matrix
B0006412biological_processtranslation
B0006418biological_processtRNA aminoacylation for protein translation
B0006422biological_processaspartyl-tRNA aminoacylation
B0016020cellular_componentmembrane
B0016874molecular_functionligase activity
B0031966cellular_componentmitochondrial membrane
B0042803molecular_functionprotein homodimerization activity
B0043039biological_processtRNA aminoacylation
B0050560molecular_functionaspartate-tRNA(Asn) ligase activity
B0070145biological_processmitochondrial asparaginyl-tRNA aminoacylation
C0000049molecular_functiontRNA binding
C0000166molecular_functionnucleotide binding
C0003676molecular_functionnucleic acid binding
C0004812molecular_functionaminoacyl-tRNA ligase activity
C0004815molecular_functionaspartate-tRNA ligase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005759cellular_componentmitochondrial matrix
C0006412biological_processtranslation
C0006418biological_processtRNA aminoacylation for protein translation
C0006422biological_processaspartyl-tRNA aminoacylation
C0016020cellular_componentmembrane
C0016874molecular_functionligase activity
C0031966cellular_componentmitochondrial membrane
C0042803molecular_functionprotein homodimerization activity
C0043039biological_processtRNA aminoacylation
C0050560molecular_functionaspartate-tRNA(Asn) ligase activity
C0070145biological_processmitochondrial asparaginyl-tRNA aminoacylation
D0000049molecular_functiontRNA binding
D0000166molecular_functionnucleotide binding
D0003676molecular_functionnucleic acid binding
D0004812molecular_functionaminoacyl-tRNA ligase activity
D0004815molecular_functionaspartate-tRNA ligase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005759cellular_componentmitochondrial matrix
D0006412biological_processtranslation
D0006418biological_processtRNA aminoacylation for protein translation
D0006422biological_processaspartyl-tRNA aminoacylation
D0016020cellular_componentmembrane
D0016874molecular_functionligase activity
D0031966cellular_componentmitochondrial membrane
D0042803molecular_functionprotein homodimerization activity
D0043039biological_processtRNA aminoacylation
D0050560molecular_functionaspartate-tRNA(Asn) ligase activity
D0070145biological_processmitochondrial asparaginyl-tRNA aminoacylation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues16
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AARG266
CGLU535
CARG542
CGLY584
DARG266
DGLU535
DARG542
DGLY584
AGLU535
AARG542
AGLY584
BARG266
BGLU535
BARG542
BGLY584
CARG266

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q3KRD0
ChainResidueDetails
ATHR219
BTHR219
CTHR219
DTHR219

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER242
BSER242
CSER242
DSER242

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS382
BLYS382
CLYS382
DLYS382

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PDB entries from 2024-10-30

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