4ABZ

TetR(D) in Complex with Tigecycline and Magnesium, co-crystallized

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000976	molecular_function	transcription cis-regulatory region binding
AAA	0003677	molecular_function	DNA binding
AAA	0003700	molecular_function	DNA-binding transcription factor activity
AAA	0006355	biological_process	regulation of DNA-templated transcription
AAA	0045892	biological_process	negative regulation of DNA-templated transcription
AAA	0046677	biological_process	response to antibiotic
AAA	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01081
Number of Residues	32
Details	HTH_TETR_1 TetR-type HTH domain signature. GIdglTTrkLaqklgIEqPtLYwHVkNKralL

Chain	Residue	Details
AAA	GLY21-LEU52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Domain: {"description":"HTH tetR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	19
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8153629","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2TRT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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