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4AA2

Crystal structure of ANCE in complex with bradykinin potentiating peptide b

Functional Information from GO Data
ChainGOidnamespacecontents
A0006508biological_processproteolysis
A0008237molecular_functionmetallopeptidase activity
A0008241molecular_functionpeptidyl-dipeptidase activity
A0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00142
Number of Residues10
DetailsZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TVHHELGHIQ
ChainResidueDetails
ATHR364-GLN373

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Angiotensin-converting enzyme active site binding; via amide nitrogen => ECO:0000269|PubMed:23056909
ChainResidueDetails
PGLY2

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|Ref.5
ChainResidueDetails
PGLU1

site_idSWS_FT_FI3
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01355
ChainResidueDetails
AHIS367
AHIS371
AGLU395

site_idSWS_FT_FI4
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305|PubMed:8761461
ChainResidueDetails
AASN53
AASN196
AASN311

227561

PDB entries from 2024-11-20

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