4A8T
Crystal structure of putrescine transcarbamylase from Enterococcus faecalis lacking its C-terminal Helix, with bound N5-(phosphonoacetyl) -L-ornithine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006591 | biological_process | ornithine metabolic process |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| A | 0033390 | biological_process | putrescine biosynthetic process from arginine via N-carbamoylputrescine |
| A | 0050231 | molecular_function | putrescine carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PAO A 1318 |
| Chain | Residue |
| A | SER52 |
| A | LEU270 |
| A | ARG297 |
| A | HOH2121 |
| A | HOH2299 |
| A | HOH2300 |
| A | HOH2302 |
| A | HOH2386 |
| A | HOH2387 |
| A | THR53 |
| A | ARG54 |
| A | THR55 |
| A | ARG103 |
| A | HIS130 |
| A | THR163 |
| A | GLN164 |
| A | ASP227 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 1319 |
| Chain | Residue |
| A | HIS69 |
| A | HIS69 |
| A | HIS69 |
| A | HOH2131 |
| A | HOH2131 |
| A | HOH2131 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 1320 |
| Chain | Residue |
| A | TYR18 |
| A | ASP21 |
| A | LEU22 |
| A | LYS25 |
| A | GLU28 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER52 | |
| A | ARG103 | |
| A | HIS130 | |
| A | HIS268 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Important for structural integrity => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS27 | |
| A | GLU143 |
