4A8H
Crystal structure of putrescine transcarbamylase from Enterococcus faecalis with N-(phosphonoacetyl)-putrescine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0019240 | biological_process | citrulline biosynthetic process |
| A | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| A | 0033390 | biological_process | putrescine biosynthetic process from arginine via N-carbamoylputrescine |
| A | 0042450 | biological_process | arginine biosynthetic process via ornithine |
| A | 0050231 | molecular_function | putrescine carbamoyltransferase activity |
| B | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0019240 | biological_process | citrulline biosynthetic process |
| B | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| B | 0033390 | biological_process | putrescine biosynthetic process from arginine via N-carbamoylputrescine |
| B | 0042450 | biological_process | arginine biosynthetic process via ornithine |
| B | 0050231 | molecular_function | putrescine carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PUW A 1341 |
| Chain | Residue |
| A | SER52 |
| A | VAL165 |
| A | ASP227 |
| A | LEU270 |
| A | ARG297 |
| A | HOH2122 |
| A | THR53 |
| A | ARG54 |
| A | THR55 |
| A | GLN79 |
| A | ARG103 |
| A | HIS130 |
| A | GLN133 |
| A | GLN164 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TRS A 1342 |
| Chain | Residue |
| A | ASP161 |
| A | ALA162 |
| A | PHE188 |
| A | GLY231 |
| A | HOH2076 |
| A | HOH2163 |
| A | HOH2164 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1343 |
| Chain | Residue |
| A | ARG91 |
| A | ARG95 |
| A | HOH2064 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1344 |
| Chain | Residue |
| A | ASN41 |
| A | GLU64 |
| A | GLY67 |
| A | HOH2032 |
| A | HOH2051 |
| A | HOH2051 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1345 |
| Chain | Residue |
| A | GLY261 |
| A | ALA262 |
| A | HOH2144 |
| B | HIS107 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 1346 |
| Chain | Residue |
| A | HIS69 |
| A | HIS69 |
| A | HIS69 |
| A | HOH2050 |
| A | HOH2050 |
| A | HOH2050 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PUW B 1341 |
| Chain | Residue |
| B | SER52 |
| B | THR53 |
| B | ARG54 |
| B | THR55 |
| B | GLN79 |
| B | ARG103 |
| B | HIS130 |
| B | GLN164 |
| B | VAL165 |
| B | ASP227 |
| B | LEU270 |
| B | ARG297 |
| B | HOH2097 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TRS B 1342 |
| Chain | Residue |
| B | ASP161 |
| B | ALA162 |
| B | PHE188 |
| B | GLY231 |
| B | LEU232 |
| B | HOH2087 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1343 |
| Chain | Residue |
| B | ARG91 |
| B | ARG95 |
| B | HOH2058 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1344 |
| Chain | Residue |
| B | GLU64 |
| B | GLY67 |
| B | HOH2027 |
| B | HOH2047 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 1345 |
| Chain | Residue |
| B | HIS69 |
| B | HIS69 |
| B | HIS69 |
| B | HOH2046 |
| B | HOH2046 |
| B | HOH2046 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER52 | |
| A | ARG103 | |
| A | HIS130 | |
| A | HIS268 | |
| B | SER52 | |
| B | ARG103 | |
| B | HIS130 | |
| B | HIS268 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Important for structural integrity => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS27 | |
| A | GLU143 | |
| B | LYS27 | |
| B | GLU143 |
