4A8D

DegP dodecamer with bound OMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006457	biological_process	protein folding
A	0006508	biological_process	proteolysis
A	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
A	0006979	biological_process	response to oxidative stress
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0009266	biological_process	response to temperature stimulus
A	0009408	biological_process	response to heat
A	0016787	molecular_function	hydrolase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0042802	molecular_function	identical protein binding
A	0051603	biological_process	proteolysis involved in protein catabolic process
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006457	biological_process	protein folding
B	0006508	biological_process	proteolysis
B	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
B	0006979	biological_process	response to oxidative stress
B	0008233	molecular_function	peptidase activity
B	0008236	molecular_function	serine-type peptidase activity
B	0009266	biological_process	response to temperature stimulus
B	0009408	biological_process	response to heat
B	0016787	molecular_function	hydrolase activity
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042597	cellular_component	periplasmic space
B	0042802	molecular_function	identical protein binding
B	0051603	biological_process	proteolysis involved in protein catabolic process
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0006457	biological_process	protein folding
C	0006508	biological_process	proteolysis
C	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
C	0006979	biological_process	response to oxidative stress
C	0008233	molecular_function	peptidase activity
C	0008236	molecular_function	serine-type peptidase activity
C	0009266	biological_process	response to temperature stimulus
C	0009408	biological_process	response to heat
C	0016787	molecular_function	hydrolase activity
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0042597	cellular_component	periplasmic space
C	0042802	molecular_function	identical protein binding
C	0051603	biological_process	proteolysis involved in protein catabolic process
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0006457	biological_process	protein folding
D	0006508	biological_process	proteolysis
D	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
D	0006979	biological_process	response to oxidative stress
D	0008233	molecular_function	peptidase activity
D	0008236	molecular_function	serine-type peptidase activity
D	0009266	biological_process	response to temperature stimulus
D	0009408	biological_process	response to heat
D	0016787	molecular_function	hydrolase activity
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0042597	cellular_component	periplasmic space
D	0042802	molecular_function	identical protein binding
D	0051603	biological_process	proteolysis involved in protein catabolic process
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006457	biological_process	protein folding
E	0006508	biological_process	proteolysis
E	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
E	0006979	biological_process	response to oxidative stress
E	0008233	molecular_function	peptidase activity
E	0008236	molecular_function	serine-type peptidase activity
E	0009266	biological_process	response to temperature stimulus
E	0009408	biological_process	response to heat
E	0016787	molecular_function	hydrolase activity
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0042597	cellular_component	periplasmic space
E	0042802	molecular_function	identical protein binding
E	0051603	biological_process	proteolysis involved in protein catabolic process
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006457	biological_process	protein folding
F	0006508	biological_process	proteolysis
F	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
F	0006979	biological_process	response to oxidative stress
F	0008233	molecular_function	peptidase activity
F	0008236	molecular_function	serine-type peptidase activity
F	0009266	biological_process	response to temperature stimulus
F	0009408	biological_process	response to heat
F	0016787	molecular_function	hydrolase activity
F	0030288	cellular_component	outer membrane-bounded periplasmic space
F	0042597	cellular_component	periplasmic space
F	0042802	molecular_function	identical protein binding
F	0051603	biological_process	proteolysis involved in protein catabolic process
G	0004252	molecular_function	serine-type endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0006457	biological_process	protein folding
G	0006508	biological_process	proteolysis
G	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
G	0006979	biological_process	response to oxidative stress
G	0008233	molecular_function	peptidase activity
G	0008236	molecular_function	serine-type peptidase activity
G	0009266	biological_process	response to temperature stimulus
G	0009408	biological_process	response to heat
G	0016787	molecular_function	hydrolase activity
G	0030288	cellular_component	outer membrane-bounded periplasmic space
G	0042597	cellular_component	periplasmic space
G	0042802	molecular_function	identical protein binding
G	0051603	biological_process	proteolysis involved in protein catabolic process
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005515	molecular_function	protein binding
H	0005886	cellular_component	plasma membrane
H	0006457	biological_process	protein folding
H	0006508	biological_process	proteolysis
H	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
H	0006979	biological_process	response to oxidative stress
H	0008233	molecular_function	peptidase activity
H	0008236	molecular_function	serine-type peptidase activity
H	0009266	biological_process	response to temperature stimulus
H	0009408	biological_process	response to heat
H	0016787	molecular_function	hydrolase activity
H	0030288	cellular_component	outer membrane-bounded periplasmic space
H	0042597	cellular_component	periplasmic space
H	0042802	molecular_function	identical protein binding
H	0051603	biological_process	proteolysis involved in protein catabolic process
I	0004252	molecular_function	serine-type endopeptidase activity
I	0005515	molecular_function	protein binding
I	0005886	cellular_component	plasma membrane
I	0006457	biological_process	protein folding
I	0006508	biological_process	proteolysis
I	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
I	0006979	biological_process	response to oxidative stress
I	0008233	molecular_function	peptidase activity
I	0008236	molecular_function	serine-type peptidase activity
I	0009266	biological_process	response to temperature stimulus
I	0009408	biological_process	response to heat
I	0016787	molecular_function	hydrolase activity
I	0030288	cellular_component	outer membrane-bounded periplasmic space
I	0042597	cellular_component	periplasmic space
I	0042802	molecular_function	identical protein binding
I	0051603	biological_process	proteolysis involved in protein catabolic process
J	0004252	molecular_function	serine-type endopeptidase activity
J	0005515	molecular_function	protein binding
J	0005886	cellular_component	plasma membrane
J	0006457	biological_process	protein folding
J	0006508	biological_process	proteolysis
J	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
J	0006979	biological_process	response to oxidative stress
J	0008233	molecular_function	peptidase activity
J	0008236	molecular_function	serine-type peptidase activity
J	0009266	biological_process	response to temperature stimulus
J	0009408	biological_process	response to heat
J	0016787	molecular_function	hydrolase activity
J	0030288	cellular_component	outer membrane-bounded periplasmic space
J	0042597	cellular_component	periplasmic space
J	0042802	molecular_function	identical protein binding
J	0051603	biological_process	proteolysis involved in protein catabolic process
K	0004252	molecular_function	serine-type endopeptidase activity
K	0005515	molecular_function	protein binding
K	0005886	cellular_component	plasma membrane
K	0006457	biological_process	protein folding
K	0006508	biological_process	proteolysis
K	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
K	0006979	biological_process	response to oxidative stress
K	0008233	molecular_function	peptidase activity
K	0008236	molecular_function	serine-type peptidase activity
K	0009266	biological_process	response to temperature stimulus
K	0009408	biological_process	response to heat
K	0016787	molecular_function	hydrolase activity
K	0030288	cellular_component	outer membrane-bounded periplasmic space
K	0042597	cellular_component	periplasmic space
K	0042802	molecular_function	identical protein binding
K	0051603	biological_process	proteolysis involved in protein catabolic process
L	0004252	molecular_function	serine-type endopeptidase activity
L	0005515	molecular_function	protein binding
L	0005886	cellular_component	plasma membrane
L	0006457	biological_process	protein folding
L	0006508	biological_process	proteolysis
L	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
L	0006979	biological_process	response to oxidative stress
L	0008233	molecular_function	peptidase activity
L	0008236	molecular_function	serine-type peptidase activity
L	0009266	biological_process	response to temperature stimulus
L	0009408	biological_process	response to heat
L	0016787	molecular_function	hydrolase activity
L	0030288	cellular_component	outer membrane-bounded periplasmic space
L	0042597	cellular_component	periplasmic space
L	0042802	molecular_function	identical protein binding
L	0051603	biological_process	proteolysis involved in protein catabolic process
M	0001618	molecular_function	virus receptor activity
M	0005515	molecular_function	protein binding
M	0006811	biological_process	monoatomic ion transport
M	0006974	biological_process	DNA damage response
M	0009279	cellular_component	cell outer membrane
M	0015288	molecular_function	porin activity
M	0016020	cellular_component	membrane
M	0034220	biological_process	monoatomic ion transmembrane transport
M	0042802	molecular_function	identical protein binding
M	0046718	biological_process	symbiont entry into host cell
M	0046813	biological_process	receptor-mediated virion attachment to host cell
M	0046872	molecular_function	metal ion binding
M	0046930	cellular_component	pore complex
M	0120010	biological_process	intermembrane phospholipid transfer

Functional Information from PROSITE/UniProt

site_id	PS00576
Number of Residues	17
Details	GRAM_NEG_PORIN General diffusion Gram-negative porins signature. VdvGatYyFnKnmSTYV

Chain	Residue	Details
M	VAL298-VAL314

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1092
Details	Domain: {"description":"PDZ 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"20581825","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	156
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	46
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"16949612","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	133
Details	Transmembrane: {"description":"Beta stranded"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	135
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"16949612","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	17
Details	Region: {"description":"Loop L3; may constrict the pore"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PDB","id":"2J1N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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