4A82
Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006869 | biological_process | lipid transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0140359 | molecular_function | ABC-type transporter activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006869 | biological_process | lipid transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0140359 | molecular_function | ABC-type transporter activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006869 | biological_process | lipid transport |
| C | 0016020 | cellular_component | membrane |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| C | 0055085 | biological_process | transmembrane transport |
| C | 0140359 | molecular_function | ABC-type transporter activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006869 | biological_process | lipid transport |
| D | 0016020 | cellular_component | membrane |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| D | 0055085 | biological_process | transmembrane transport |
| D | 0140359 | molecular_function | ABC-type transporter activity |
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQKQRLSIARIF |
| Chain | Residue | Details |
| A | LEU478-PHE492 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1684 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-ARG15 | |
| C | ARG81-GLY138 | |
| C | ARG184-ASN244 | |
| C | GLU288-LEU578 | |
| D | MET1-ARG15 | |
| D | ARG81-GLY138 | |
| D | ARG184-ASN244 | |
| D | GLU288-LEU578 | |
| A | ARG81-GLY138 | |
| A | ARG184-ASN244 | |
| A | GLU288-LEU578 | |
| B | MET1-ARG15 | |
| B | ARG81-GLY138 | |
| B | ARG184-ASN244 | |
| B | GLU288-LEU578 | |
| C | MET1-ARG15 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 460 |
| Details | TRANSMEM: Helical => ECO:0000255|PROSITE-ProRule:PRU00441 |
| Chain | Residue | Details |
| A | ILE16-LEU36 | |
| B | LEU163-GLY183 | |
| B | ALA245-ILE263 | |
| B | ALA270-LEU287 | |
| C | ILE16-LEU36 | |
| C | THR60-ILE80 | |
| C | LEU139-LEU159 | |
| C | LEU163-GLY183 | |
| C | ALA245-ILE263 | |
| C | ALA270-LEU287 | |
| D | ILE16-LEU36 | |
| A | THR60-ILE80 | |
| D | THR60-ILE80 | |
| D | LEU139-LEU159 | |
| D | LEU163-GLY183 | |
| D | ALA245-ILE263 | |
| D | ALA270-LEU287 | |
| A | LEU139-LEU159 | |
| A | LEU163-GLY183 | |
| A | ALA245-ILE263 | |
| A | ALA270-LEU287 | |
| B | ILE16-LEU36 | |
| B | THR60-ILE80 | |
| B | LEU139-LEU159 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 116 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE37-LEU59 | |
| D | ILE37-LEU59 | |
| D | ASP160-LYS162 | |
| D | GLY264-LEU269 | |
| A | ASP160-LYS162 | |
| A | GLY264-LEU269 | |
| B | ILE37-LEU59 | |
| B | ASP160-LYS162 | |
| B | GLY264-LEU269 | |
| C | ILE37-LEU59 | |
| C | ASP160-LYS162 | |
| C | GLY264-LEU269 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434 |
| Chain | Residue | Details |
| A | GLY374 | |
| B | GLY374 | |
| C | GLY374 | |
| D | GLY374 |
