4A6Q

Crystal structure of mouse SAP18 residues 6-143

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000118	cellular_component	histone deacetylase complex
A	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005667	cellular_component	transcription regulator complex
A	0005737	cellular_component	cytoplasm
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006397	biological_process	mRNA processing
A	0008380	biological_process	RNA splicing
A	0016607	cellular_component	nuclear speck
A	0043065	biological_process	positive regulation of apoptotic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
A	0061574	cellular_component	ASAP complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A 1144

Chain	Residue
A	THR34
A	THR35
A	TYR77

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD A 1145

Chain	Residue
A	ILE91
A	GLN125
A	LYS126
A	ARG142
A	HOH2168

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:O00422

Chain	Residue	Details
A	LYS13

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