4A46

Crosstalk between Cu(I) and Zn(II) homeostasis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0046872	molecular_function	metal ion binding
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0046872	molecular_function	metal ion binding
C	0005507	molecular_function	copper ion binding
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0046872	molecular_function	metal ion binding
D	0005507	molecular_function	copper ion binding
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 65

Chain	Residue
A	CYS12
A	CYS15
B	CYS12
B	CYS15

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA A 1065

Chain	Residue
A	HOH2016
C	HOH2040

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 65

Chain	Residue
D	CYS15
C	CYS12
C	CYS15
D	CYS12

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 1065

Chain	Residue
A	GLN51
C	GLN29

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA C 1066

Chain	Residue
A	HOH2025
C	HOH2027
C	HOH2038
C	HOH2039

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 1065

Chain	Residue
B	LEU36
D	LEU36

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Functional Information from PROSITE/UniProt

site_id	PS01047
Number of Residues	30
Details	HMA_1 Heavy-metal-associated domain. VpTIaCeACaeaVTkaVqnedaqatvq.VdL

Chain	Residue	Details
A	VAL7-LEU36

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