Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005774 | cellular_component | vacuolar membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0009678 | molecular_function | diphosphate hydrolysis-driven proton transmembrane transporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005774 | cellular_component | vacuolar membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0009678 | molecular_function | diphosphate hydrolysis-driven proton transmembrane transporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 1767 |
| Chain | Residue |
| A | ASP253 |
| A | ASP257 |
| A | MG1769 |
| A | 2PN1773 |
| A | HOH2108 |
| A | HOH2109 |
| A | HOH2112 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 1768 |
| Chain | Residue |
| A | 2PN1773 |
| A | HOH2127 |
| A | HOH2128 |
| A | HOH2129 |
| A | HOH2134 |
| A | ASP507 |
| A | MG1770 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 1769 |
| Chain | Residue |
| A | ASP253 |
| A | ASP727 |
| A | LYS730 |
| A | MG1767 |
| A | 2PN1773 |
| A | HOH2109 |
| A | HOH2299 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1770 |
| Chain | Residue |
| A | ASP283 |
| A | ASP507 |
| A | MG1768 |
| A | 2PN1773 |
| A | HOH2106 |
| A | HOH2134 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1771 |
| Chain | Residue |
| A | ASN534 |
| A | ASP691 |
| A | 2PN1773 |
| A | HOH2216 |
| A | HOH2234 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 1772 |
| Chain | Residue |
| A | ASN534 |
| A | 2PN1773 |
| A | HOH2137 |
| A | HOH2214 |
| A | HOH2236 |
| site_id | AC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE 2PN A 1773 |
| Chain | Residue |
| A | LYS250 |
| A | ASP253 |
| A | GLU268 |
| A | ASP283 |
| A | ASP287 |
| A | ASP507 |
| A | ASN534 |
| A | ASP691 |
| A | LYS694 |
| A | ASP727 |
| A | LYS730 |
| A | ASP731 |
| A | MG1767 |
| A | MG1768 |
| A | MG1769 |
| A | MG1770 |
| A | MG1771 |
| A | K1772 |
| A | HOH2105 |
| A | HOH2106 |
| A | HOH2109 |
| A | HOH2112 |
| A | HOH2128 |
| A | HOH2134 |
| A | HOH2137 |
| A | HOH2216 |
| A | HOH2234 |
| A | HOH2236 |
| A | HOH2299 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 1767 |
| Chain | Residue |
| B | ASP253 |
| B | ASP257 |
| B | MG1769 |
| B | 2PN1773 |
| B | HOH2072 |
| B | HOH2073 |
| B | HOH2075 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 1768 |
| Chain | Residue |
| B | ASP507 |
| B | MG1770 |
| B | 2PN1773 |
| B | HOH2087 |
| B | HOH2088 |
| B | HOH2089 |
| B | HOH2094 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 1769 |
| Chain | Residue |
| B | ASP253 |
| B | ASP727 |
| B | LYS730 |
| B | MG1767 |
| B | 2PN1773 |
| B | HOH2072 |
| B | HOH2232 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1770 |
| Chain | Residue |
| B | ASP283 |
| B | ASP507 |
| B | MG1768 |
| B | 2PN1773 |
| B | HOH2070 |
| B | HOH2094 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1771 |
| Chain | Residue |
| B | ASN534 |
| B | ASP691 |
| B | K1772 |
| B | 2PN1773 |
| B | HOH2169 |
| B | HOH2179 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K B 1772 |
| Chain | Residue |
| B | ASN534 |
| B | MG1771 |
| B | 2PN1773 |
| B | HOH2098 |
| B | HOH2167 |
| B | HOH2169 |
| B | HOH2181 |
| site_id | BC5 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE 2PN B 1773 |
| Chain | Residue |
| B | LYS250 |
| B | ASP253 |
| B | ASP283 |
| B | ASP287 |
| B | ASP507 |
| B | ASN534 |
| B | ASP691 |
| B | LYS694 |
| B | ASP727 |
| B | LYS730 |
| B | ASP731 |
| B | MG1767 |
| B | MG1768 |
| B | MG1769 |
| B | MG1770 |
| B | MG1771 |
| B | K1772 |
| B | HOH2069 |
| B | HOH2070 |
| B | HOH2072 |
| B | HOH2075 |
| B | HOH2087 |
| B | HOH2088 |
| B | HOH2094 |
| B | HOH2098 |
| B | HOH2169 |
| B | HOH2179 |
| B | HOH2181 |
| B | HOH2232 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMU A 1774 |
| Chain | Residue |
| A | LYS362 |
| A | TYR424 |
| A | TYR430 |
| A | ALA465 |
| A | HOH2164 |
| A | HOH2324 |
| A | HOH2325 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMU B 1774 |
| Chain | Residue |
| A | LYS457 |
| B | TRP588 |
| B | LYS640 |
| B | GLU641 |
| B | THR652 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMU A 1775 |
| Chain | Residue |
| A | TRP588 |
| A | MET592 |
| A | THR652 |
| B | LYS457 |
| B | DMU1777 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMU A 1776 |
| Chain | Residue |
| A | TYR95 |
| A | PHE99 |
| A | ASP636 |
| A | HOH2040 |
| A | HOH2326 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMU B 1775 |
| Chain | Residue |
| B | SER401 |
| B | TRP402 |
| B | HOH2140 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMU B 1776 |
| Chain | Residue |
| A | GLN403 |
| B | PHE660 |
| B | PHE763 |
| B | HOH2255 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMU A 1777 |
| Chain | Residue |
| A | ILE577 |
| A | PHE660 |
| A | LEU762 |
| A | HOH2328 |
| A | HOH2329 |
| B | DMU1777 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMU A 1778 |
| Chain | Residue |
| A | GLY116 |
| A | HIS758 |
| A | HOH2331 |
| A | HOH2332 |
| A | HOH2333 |
| A | HOH2334 |
| A | HOH2335 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DMU B 1777 |
| Chain | Residue |
| A | TRP588 |
| A | DMU1775 |
| A | DMU1777 |
| B | TYR424 |
| B | TYR425 |
| B | LYS457 |
| B | ILE461 |
| B | HOH2256 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 148 |
| Details | Topological domain: {"description":"Intravacuolar","evidences":[{"source":"PubMed","id":"22456709","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 850 |
| Details | Transmembrane: {"description":"Helical"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 370 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"22456709","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22456709","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Site: {"description":"Important for proton transport","evidences":[{"evidenceCode":"ECO:0000305"}]} |
