3ZXW
STRUCTURE OF ACTIVATED RUBISCO FROM THERMOSYNECHOCOCCUS ELONGATUS COMPLEXED WITH 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009853 | biological_process | photorespiration |
| A | 0015977 | biological_process | carbon fixation |
| A | 0015979 | biological_process | photosynthesis |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| A | 0019253 | biological_process | reductive pentose-phosphate cycle |
| A | 0031470 | cellular_component | carboxysome |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0009853 | biological_process | photorespiration |
| B | 0015977 | biological_process | carbon fixation |
| B | 0015979 | biological_process | photosynthesis |
| B | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| B | 0019253 | biological_process | reductive pentose-phosphate cycle |
| B | 0031470 | cellular_component | carboxysome |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0009853 | biological_process | photorespiration |
| C | 0015977 | biological_process | carbon fixation |
| C | 0015979 | biological_process | photosynthesis |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| C | 0019253 | biological_process | reductive pentose-phosphate cycle |
| C | 0031470 | cellular_component | carboxysome |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0009853 | biological_process | photorespiration |
| D | 0015977 | biological_process | carbon fixation |
| D | 0015979 | biological_process | photosynthesis |
| D | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| D | 0019253 | biological_process | reductive pentose-phosphate cycle |
| D | 0031470 | cellular_component | carboxysome |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0009853 | biological_process | photorespiration |
| E | 0015977 | biological_process | carbon fixation |
| E | 0015979 | biological_process | photosynthesis |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| E | 0019253 | biological_process | reductive pentose-phosphate cycle |
| E | 0031470 | cellular_component | carboxysome |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0009853 | biological_process | photorespiration |
| F | 0015977 | biological_process | carbon fixation |
| F | 0015979 | biological_process | photosynthesis |
| F | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| F | 0019253 | biological_process | reductive pentose-phosphate cycle |
| F | 0031470 | cellular_component | carboxysome |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0004497 | molecular_function | monooxygenase activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0009853 | biological_process | photorespiration |
| G | 0015977 | biological_process | carbon fixation |
| G | 0015979 | biological_process | photosynthesis |
| G | 0016829 | molecular_function | lyase activity |
| G | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| G | 0019253 | biological_process | reductive pentose-phosphate cycle |
| G | 0031470 | cellular_component | carboxysome |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0009853 | biological_process | photorespiration |
| H | 0015977 | biological_process | carbon fixation |
| H | 0015979 | biological_process | photosynthesis |
| H | 0016984 | molecular_function | ribulose-bisphosphate carboxylase activity |
| H | 0019253 | biological_process | reductive pentose-phosphate cycle |
| H | 0031470 | cellular_component | carboxysome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 476 |
| Chain | Residue |
| A | LYS177 |
| A | KCX201 |
| A | ASP203 |
| A | GLU204 |
| A | CAP477 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE CAP A 477 |
| Chain | Residue |
| A | ASP203 |
| A | GLU204 |
| A | HIS294 |
| A | ARG295 |
| A | HIS327 |
| A | LYS334 |
| A | LEU335 |
| A | SER379 |
| A | GLY380 |
| A | GLY381 |
| A | GLY403 |
| A | GLY404 |
| A | MG476 |
| A | HOH2105 |
| A | HOH2170 |
| A | HOH2171 |
| A | HOH2182 |
| A | HOH2216 |
| A | HOH2217 |
| A | HOH2231 |
| E | GLU60 |
| E | THR65 |
| E | TRP66 |
| E | ASN123 |
| E | HOH2028 |
| A | THR173 |
| A | LYS175 |
| A | LYS177 |
| A | KCX201 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 476 |
| Chain | Residue |
| C | KCX201 |
| C | ASP203 |
| C | GLU204 |
| C | CAP477 |
| site_id | AC4 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE CAP C 477 |
| Chain | Residue |
| C | GLU60 |
| C | THR65 |
| C | TRP66 |
| C | ASN123 |
| C | THR173 |
| C | LYS175 |
| C | LYS177 |
| C | KCX201 |
| C | ASP203 |
| C | GLU204 |
| C | HIS294 |
| C | ARG295 |
| C | HIS327 |
| C | LYS334 |
| C | LEU335 |
| C | SER379 |
| C | GLY380 |
| C | GLY381 |
| C | GLY403 |
| C | GLY404 |
| C | MG476 |
| C | HOH2038 |
| C | HOH2077 |
| C | HOH2116 |
| C | HOH2160 |
| C | HOH2161 |
| C | HOH2173 |
| C | HOH2206 |
| C | HOH2207 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG E 476 |
| Chain | Residue |
| E | KCX201 |
| E | ASP203 |
| E | GLU204 |
| E | CAP477 |
| site_id | AC6 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE CAP E 477 |
| Chain | Residue |
| A | GLU60 |
| A | THR65 |
| A | TRP66 |
| A | ASN123 |
| A | HOH2068 |
| E | THR173 |
| E | LYS175 |
| E | LYS177 |
| E | KCX201 |
| E | ASP203 |
| E | GLU204 |
| E | HIS294 |
| E | ARG295 |
| E | HIS327 |
| E | LYS334 |
| E | LEU335 |
| E | SER379 |
| E | GLY380 |
| E | GLY381 |
| E | GLY403 |
| E | GLY404 |
| E | MG476 |
| E | HOH2142 |
| E | HOH2143 |
| E | HOH2154 |
| E | HOH2188 |
| E | HOH2189 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG G 476 |
| Chain | Residue |
| G | ASP203 |
| G | GLU204 |
| G | CAP477 |
| G | KCX201 |
| site_id | AC8 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE CAP G 477 |
| Chain | Residue |
| G | GLU60 |
| G | THR65 |
| G | TRP66 |
| G | ASN123 |
| G | THR173 |
| G | LYS175 |
| G | LYS177 |
| G | KCX201 |
| G | ASP203 |
| G | GLU204 |
| G | HIS294 |
| G | ARG295 |
| G | HIS327 |
| G | LYS334 |
| G | LEU335 |
| G | SER379 |
| G | GLY380 |
| G | GLY381 |
| G | GLY403 |
| G | GLY404 |
| G | MG476 |
| G | HOH2041 |
| G | HOH2141 |
| G | HOH2142 |
| G | HOH2143 |
| G | HOH2154 |
| G | HOH2156 |
| G | HOH2186 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1476 |
| Chain | Residue |
| C | LYS18 |
| C | THR65 |
| C | TRP66 |
| C | THR67 |
| C | THR68 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1476 |
| Chain | Residue |
| A | LYS18 |
| A | TYR24 |
| A | TRP66 |
| A | THR67 |
| A | THR68 |
| A | HOH2007 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL E 1476 |
| Chain | Residue |
| E | VAL17 |
| E | LYS18 |
| E | TYR20 |
| E | TYR24 |
| E | THR65 |
| E | TRP66 |
| E | THR67 |
| E | THR68 |
| E | HOH2010 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL G 1476 |
| Chain | Residue |
| G | LYS18 |
| G | TYR24 |
| G | THR65 |
| G | TRP66 |
| G | THR67 |
| G | THR68 |
| G | HOH2006 |
| G | HOH2040 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL E 1477 |
| Chain | Residue |
| E | ARG295 |
| E | HIS298 |
| E | ASP302 |
| E | ASP473 |
| E | HOH2159 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1477 |
| Chain | Residue |
| A | ARG295 |
| A | HIS298 |
| A | ASP302 |
| A | GLU336 |
| A | ASP473 |
| A | HOH2183 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 1478 |
| Chain | Residue |
| A | GLU88 |
| A | HOH2232 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1477 |
| Chain | Residue |
| C | ASP86 |
| C | ILE87 |
| C | GLU88 |
| E | ASP86 |
| E | ILE87 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1479 |
| Chain | Residue |
| A | ARG215 |
| A | PHE256 |
| A | GLU259 |
| A | HOH2146 |
| A | HOH2235 |
| G | ASP286 |
| G | ASN287 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 1478 |
| Chain | Residue |
| C | LYS258 |
| C | GLU261 |
| C | MET262 |
| C | PRO263 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1479 |
| Chain | Residue |
| C | ARG295 |
| C | HIS298 |
| C | ASP302 |
| C | GLU336 |
| C | ASP473 |
Functional Information from PROSITE/UniProt
| site_id | PS00157 |
| Number of Residues | 9 |
| Details | RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE |
| Chain | Residue | Details |
| A | GLY196-GLU204 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01338 |
| Chain | Residue | Details |
| A | LYS175 | |
| A | HIS294 | |
| C | LYS175 | |
| C | HIS294 | |
| E | LYS175 | |
| E | HIS294 | |
| G | LYS175 | |
| G | HIS294 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: in homodimeric partner => ECO:0000255|HAMAP-Rule:MF_01338 |
| Chain | Residue | Details |
| E | ASN123 | |
| G | ASN123 | |
| A | ASN123 | |
| C | ASN123 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01338 |
| Chain | Residue | Details |
| C | LYS177 | |
| C | ASP203 | |
| C | GLU204 | |
| C | ARG295 | |
| C | HIS327 | |
| C | SER379 | |
| E | THR173 | |
| E | LYS177 | |
| E | ASP203 | |
| E | GLU204 | |
| E | ARG295 | |
| E | HIS327 | |
| E | SER379 | |
| G | THR173 | |
| G | LYS177 | |
| G | ASP203 | |
| G | GLU204 | |
| G | ARG295 | |
| G | HIS327 | |
| G | SER379 | |
| C | THR173 | |
| A | THR173 | |
| A | LYS177 | |
| A | ASP203 | |
| A | GLU204 | |
| A | ARG295 | |
| A | HIS327 | |
| A | SER379 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: via carbamate group => ECO:0000255|HAMAP-Rule:MF_01338 |
| Chain | Residue | Details |
| C | KCX201 | |
| E | KCX201 | |
| G | KCX201 | |
| A | KCX201 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01338 |
| Chain | Residue | Details |
| C | LYS334 | |
| E | LYS334 | |
| G | LYS334 | |
| A | LYS334 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-carboxylysine => ECO:0000255|HAMAP-Rule:MF_01338 |
| Chain | Residue | Details |
| C | KCX201 | |
| E | KCX201 | |
| G | KCX201 | |
| A | KCX201 |
