Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3ZXW

STRUCTURE OF ACTIVATED RUBISCO FROM THERMOSYNECHOCOCCUS ELONGATUS COMPLEXED WITH 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0009853	biological_process	photorespiration
A	0015977	biological_process	carbon fixation
A	0015979	biological_process	photosynthesis
A	0016491	molecular_function	oxidoreductase activity
A	0016829	molecular_function	lyase activity
A	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
A	0019253	biological_process	reductive pentose-phosphate cycle
A	0031470	cellular_component	carboxysome
A	0046872	molecular_function	metal ion binding
B	0009853	biological_process	photorespiration
B	0015977	biological_process	carbon fixation
B	0015979	biological_process	photosynthesis
B	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
B	0019253	biological_process	reductive pentose-phosphate cycle
B	0031470	cellular_component	carboxysome
C	0000287	molecular_function	magnesium ion binding
C	0004497	molecular_function	monooxygenase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0009853	biological_process	photorespiration
C	0015977	biological_process	carbon fixation
C	0015979	biological_process	photosynthesis
C	0016491	molecular_function	oxidoreductase activity
C	0016829	molecular_function	lyase activity
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
C	0031470	cellular_component	carboxysome
C	0046872	molecular_function	metal ion binding
D	0009853	biological_process	photorespiration
D	0015977	biological_process	carbon fixation
D	0015979	biological_process	photosynthesis
D	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
D	0019253	biological_process	reductive pentose-phosphate cycle
D	0031470	cellular_component	carboxysome
E	0000287	molecular_function	magnesium ion binding
E	0004497	molecular_function	monooxygenase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0009853	biological_process	photorespiration
E	0015977	biological_process	carbon fixation
E	0015979	biological_process	photosynthesis
E	0016491	molecular_function	oxidoreductase activity
E	0016829	molecular_function	lyase activity
E	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
E	0019253	biological_process	reductive pentose-phosphate cycle
E	0031470	cellular_component	carboxysome
E	0046872	molecular_function	metal ion binding
F	0009853	biological_process	photorespiration
F	0015977	biological_process	carbon fixation
F	0015979	biological_process	photosynthesis
F	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
F	0019253	biological_process	reductive pentose-phosphate cycle
F	0031470	cellular_component	carboxysome
G	0000287	molecular_function	magnesium ion binding
G	0004497	molecular_function	monooxygenase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0009853	biological_process	photorespiration
G	0015977	biological_process	carbon fixation
G	0015979	biological_process	photosynthesis
G	0016491	molecular_function	oxidoreductase activity
G	0016829	molecular_function	lyase activity
G	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
G	0019253	biological_process	reductive pentose-phosphate cycle
G	0031470	cellular_component	carboxysome
G	0046872	molecular_function	metal ion binding
H	0009853	biological_process	photorespiration
H	0015977	biological_process	carbon fixation
H	0015979	biological_process	photosynthesis
H	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
H	0019253	biological_process	reductive pentose-phosphate cycle
H	0031470	cellular_component	carboxysome

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 476

Chain	Residue
A	LYS177
A	KCX201
A	ASP203
A	GLU204
A	CAP477

site_id	AC2
Number of Residues	29
Details	BINDING SITE FOR RESIDUE CAP A 477

Chain	Residue
A	ASP203
A	GLU204
A	HIS294
A	ARG295
A	HIS327
A	LYS334
A	LEU335
A	SER379
A	GLY380
A	GLY381
A	GLY403
A	GLY404
A	MG476
A	HOH2105
A	HOH2170
A	HOH2171
A	HOH2182
A	HOH2216
A	HOH2217
A	HOH2231
E	GLU60
E	THR65
E	TRP66
E	ASN123
E	HOH2028
A	THR173
A	LYS175
A	LYS177
A	KCX201

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 476

Chain	Residue
C	KCX201
C	ASP203
C	GLU204
C	CAP477

site_id	AC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE CAP C 477

Chain	Residue
C	GLU60
C	THR65
C	TRP66
C	ASN123
C	THR173
C	LYS175
C	LYS177
C	KCX201
C	ASP203
C	GLU204
C	HIS294
C	ARG295
C	HIS327
C	LYS334
C	LEU335
C	SER379
C	GLY380
C	GLY381
C	GLY403
C	GLY404
C	MG476
C	HOH2038
C	HOH2077
C	HOH2116
C	HOH2160
C	HOH2161
C	HOH2173
C	HOH2206
C	HOH2207

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 476

Chain	Residue
E	KCX201
E	ASP203
E	GLU204
E	CAP477

site_id	AC6
Number of Residues	27
Details	BINDING SITE FOR RESIDUE CAP E 477

Chain	Residue
A	GLU60
A	THR65
A	TRP66
A	ASN123
A	HOH2068
E	THR173
E	LYS175
E	LYS177
E	KCX201
E	ASP203
E	GLU204
E	HIS294
E	ARG295
E	HIS327
E	LYS334
E	LEU335
E	SER379
E	GLY380
E	GLY381
E	GLY403
E	GLY404
E	MG476
E	HOH2142
E	HOH2143
E	HOH2154
E	HOH2188
E	HOH2189

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG G 476

Chain	Residue
G	ASP203
G	GLU204
G	CAP477
G	KCX201

site_id	AC8
Number of Residues	28
Details	BINDING SITE FOR RESIDUE CAP G 477

Chain	Residue
G	GLU60
G	THR65
G	TRP66
G	ASN123
G	THR173
G	LYS175
G	LYS177
G	KCX201
G	ASP203
G	GLU204
G	HIS294
G	ARG295
G	HIS327
G	LYS334
G	LEU335
G	SER379
G	GLY380
G	GLY381
G	GLY403
G	GLY404
G	MG476
G	HOH2041
G	HOH2141
G	HOH2142
G	HOH2143
G	HOH2154
G	HOH2156
G	HOH2186

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 1476

Chain	Residue
C	LYS18
C	THR65
C	TRP66
C	THR67
C	THR68

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1476

Chain	Residue
A	LYS18
A	TYR24
A	TRP66
A	THR67
A	THR68
A	HOH2007

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL E 1476

Chain	Residue
E	VAL17
E	LYS18
E	TYR20
E	TYR24
E	THR65
E	TRP66
E	THR67
E	THR68
E	HOH2010

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL G 1476

Chain	Residue
G	LYS18
G	TYR24
G	THR65
G	TRP66
G	THR67
G	THR68
G	HOH2006
G	HOH2040

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL E 1477

Chain	Residue
E	ARG295
E	HIS298
E	ASP302
E	ASP473
E	HOH2159

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1477

Chain	Residue
A	ARG295
A	HIS298
A	ASP302
A	GLU336
A	ASP473
A	HOH2183

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 1478

Chain	Residue
A	GLU88
A	HOH2232

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 1477

Chain	Residue
C	ASP86
C	ILE87
C	GLU88
E	ASP86
E	ILE87

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1479

Chain	Residue
A	ARG215
A	PHE256
A	GLU259
A	HOH2146
A	HOH2235
G	ASP286
G	ASN287

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 1478

Chain	Residue
C	LYS258
C	GLU261
C	MET262
C	PRO263

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 1479

Chain	Residue
C	ARG295
C	HIS298
C	ASP302
C	GLU336
C	ASP473

Functional Information from PROSITE/UniProt

site_id	PS00157
Number of Residues	9
Details	RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE

Chain	Residue	Details
A	GLY196-GLU204

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01338","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"description":"in homodimeric partner","evidences":[{"source":"HAMAP-Rule","id":"MF_01338","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01338","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"HAMAP-Rule","id":"MF_01338","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01338","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01338","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)