3ZXT

Dimeric structure of DAPK-1 catalytic domain in complex with AMPPCP- Mg

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
B	0004672	molecular_function	protein kinase activity
B	0005524	molecular_function	ATP binding
B	0006468	biological_process	protein phosphorylation
C	0004672	molecular_function	protein kinase activity
C	0005524	molecular_function	ATP binding
C	0006468	biological_process	protein phosphorylation
D	0004672	molecular_function	protein kinase activity
D	0005524	molecular_function	ATP binding
D	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE ACP A 1277

Chain	Residue
A	LEU19
A	VAL96
A	GLU100
A	GLU143
A	ASN144
A	MET146
A	ILE160
A	ASP161
A	MG1278
A	MG1279
A	HOH2003
A	GLY22
A	HOH2015
A	HOH2031
A	GLN23
A	PHE24
A	VAL27
A	ALA40
A	LYS42
A	ILE77
A	GLU94

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 1277

Chain	Residue
C	ASN144
C	ASP161
C	ACP1278

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ACP C 1278

Chain	Residue
C	GLY22
C	VAL27
C	ALA40
C	LYS42
C	GLU64
C	GLU94
C	VAL96
C	GLU100
C	GLU143
C	ASN144
C	MET146
C	ILE160
C	ASP161
C	MG1277
C	HOH2005
C	HOH2019

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1278

Chain	Residue
A	ASN144
A	ASP161
A	ACP1277

---

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ACP D 1277

Chain	Residue
D	LEU19
D	GLY22
D	GLN23
D	LYS42
D	ILE77
D	GLU94
D	VAL96
D	MET146
D	ILE160
D	ASP161
D	MG1278
D	HOH2035

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1279

Chain	Residue
A	ASP161
A	ACP1277
A	HOH2031

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 1277

Chain	Residue
B	GLU143
B	ASN144
B	ASP161
B	ACP1279

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 1278

Chain	Residue
D	GLU143
D	ASN144
D	ASP161
D	ACP1277

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 1278

Chain	Residue
B	ASP161
B	ACP1279

---

site_id	BC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ACP B 1279

Chain	Residue
B	LEU19
B	GLY22
B	GLN23
B	PHE24
B	ALA25
B	VAL27
B	ALA40
B	LYS42
B	ILE77
B	GLU94
B	VAL96
B	GLU100
B	GLU143
B	ASN144
B	MET146
B	ILE160
B	ASP161
B	MG1277
B	MG1278

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	28
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGSGQFAVVKkCrekstglqyaak......FIKK

Chain	Residue	Details
A	LEU19-LYS46

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IaHfDLKpeNIML

Chain	Residue	Details
A	ILE135-LEU147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	44
Details	Binding site: {}

Chain

Residue

Details

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