Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 1200 |
Chain | Residue |
B | TRP106 |
B | HOH2095 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 1100 |
Chain | Residue |
A | THR74 |
A | ASN88 |
A | HOH2045 |
B | ARG141 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 1201 |
Chain | Residue |
B | THR174 |
B | ASN188 |
B | HOH2113 |
site_id | AC4 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE EQM B 1202 |
Chain | Residue |
A | ARG8 |
A | ASP25 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ILE47 |
A | GLY48 |
A | GLY49 |
A | HOH2098 |
B | LEU123 |
B | ASP125 |
B | GLY127 |
B | ALA128 |
B | ASP129 |
B | GLY148 |
B | GLY149 |
B | ILE150 |
B | HOH2088 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
Chain | Residue | Details |
A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP25 | |
B | ASP125 | |
Chain | Residue | Details |
A | PHE99 | |
B | PHE199 | |