3ZP4

Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004106	molecular_function	chorismate mutase activity
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0046417	biological_process	chorismate metabolic process
B	0004106	molecular_function	chorismate mutase activity
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0046417	biological_process	chorismate metabolic process
C	0004106	molecular_function	chorismate mutase activity
C	0005737	cellular_component	cytoplasm
C	0008652	biological_process	amino acid biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0016853	molecular_function	isomerase activity
C	0046417	biological_process	chorismate metabolic process
D	0004106	molecular_function	chorismate mutase activity
D	0005737	cellular_component	cytoplasm
D	0008652	biological_process	amino acid biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0016853	molecular_function	isomerase activity
D	0046417	biological_process	chorismate metabolic process
E	0004106	molecular_function	chorismate mutase activity
E	0005737	cellular_component	cytoplasm
E	0008652	biological_process	amino acid biosynthetic process
E	0009073	biological_process	aromatic amino acid family biosynthetic process
E	0016853	molecular_function	isomerase activity
E	0046417	biological_process	chorismate metabolic process
F	0004106	molecular_function	chorismate mutase activity
F	0005737	cellular_component	cytoplasm
F	0008652	biological_process	amino acid biosynthetic process
F	0009073	biological_process	aromatic amino acid family biosynthetic process
F	0016853	molecular_function	isomerase activity
F	0046417	biological_process	chorismate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TSA C 1118

Chain	Residue
A	ARG7
C	CYS75
A	GLU78
A	CIR90
A	TYR108
C	PHE57
C	ALA59
C	ARG63
C	VAL73
C	THR74

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TSA B 1118

Chain	Residue
B	PHE57
B	ALA59
B	LYS60
B	VAL73
B	THR74
B	CYS75
B	HOH2036
C	ARG7
C	GLU78
C	CIR90
C	TYR108
C	LEU115

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TSA F 1118

Chain	Residue
D	ARG7
D	GLU78
D	CIR90
D	TYR108
D	LEU115
F	PHE57
F	ALA59
F	LYS60
F	VAL73
F	THR74
F	CYS75

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TSA D 1118

Chain	Residue
D	PHE57
D	ALA59
D	LYS60
D	ARG63
D	VAL73
D	THR74
D	CYS75
E	ARG7
E	GLU78
E	CIR90
E	TYR108
E	LEU115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:8046752, ECO:0007744|PDB:1COM

Chain	Residue	Details
A	ARG7
C	THR74
C	CIR90
C	TYR108
D	ARG7
D	THR74
D	CIR90
D	TYR108
E	ARG7
E	THR74
E	CIR90
A	THR74
E	TYR108
F	ARG7
F	THR74
F	CIR90
F	TYR108
A	CIR90
A	TYR108
B	ARG7
B	THR74
B	CIR90
B	TYR108
C	ARG7

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	7
Details	M-CSA 474

Chain	Residue	Details
A	ARG7	transition state stabiliser
A	ARG63	transition state stabiliser
A	CYS75	transition state stabiliser
A	GLU78	transition state stabiliser
A	CIR90	transition state stabiliser
A	TYR108	transition state stabiliser
A	ARG116	transition state stabiliser

---

site_id	MCSA2
Number of Residues	7
Details	M-CSA 474

Chain	Residue	Details
B	ARG7	transition state stabiliser
B	ARG63	transition state stabiliser
B	CYS75	transition state stabiliser
B	GLU78	transition state stabiliser
B	CIR90	transition state stabiliser
B	TYR108	transition state stabiliser
B	ARG116	transition state stabiliser

---

site_id	MCSA3
Number of Residues	7
Details	M-CSA 474

Chain	Residue	Details
C	ARG7	transition state stabiliser
C	ARG63	transition state stabiliser
C	CYS75	transition state stabiliser
C	GLU78	transition state stabiliser
C	CIR90	transition state stabiliser
C	TYR108	transition state stabiliser
C	ARG116	transition state stabiliser

---

site_id	MCSA4
Number of Residues	7
Details	M-CSA 474

Chain	Residue	Details
D	ARG7	transition state stabiliser
D	ARG63	transition state stabiliser
D	CYS75	transition state stabiliser
D	GLU78	transition state stabiliser
D	CIR90	transition state stabiliser
D	TYR108	transition state stabiliser
D	ARG116	transition state stabiliser

---

site_id	MCSA5
Number of Residues	7
Details	M-CSA 474

Chain	Residue	Details
E	ARG7	transition state stabiliser
E	ARG63	transition state stabiliser
E	CYS75	transition state stabiliser
E	GLU78	transition state stabiliser
E	CIR90	transition state stabiliser
E	TYR108	transition state stabiliser
E	ARG116	transition state stabiliser

---

site_id	MCSA6
Number of Residues	7
Details	M-CSA 474

Chain	Residue	Details
F	ARG7	transition state stabiliser
F	ARG63	transition state stabiliser
F	CYS75	transition state stabiliser
F	GLU78	transition state stabiliser
F	CIR90	transition state stabiliser
F	TYR108	transition state stabiliser
F	ARG116	transition state stabiliser

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