3ZNJ
Crystal structure of unliganded ClcF from R.opacus 1CP in crystal form 1.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 1 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 1 | 0016853 | molecular_function | isomerase activity |
| 1 | 0042952 | biological_process | beta-ketoadipate pathway |
| 2 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 2 | 0016853 | molecular_function | isomerase activity |
| 2 | 0042952 | biological_process | beta-ketoadipate pathway |
| 3 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 3 | 0016853 | molecular_function | isomerase activity |
| 3 | 0042952 | biological_process | beta-ketoadipate pathway |
| 4 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 4 | 0016853 | molecular_function | isomerase activity |
| 4 | 0042952 | biological_process | beta-ketoadipate pathway |
| 5 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 5 | 0016853 | molecular_function | isomerase activity |
| 5 | 0042952 | biological_process | beta-ketoadipate pathway |
| 6 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 6 | 0016853 | molecular_function | isomerase activity |
| 6 | 0042952 | biological_process | beta-ketoadipate pathway |
| 7 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 7 | 0016853 | molecular_function | isomerase activity |
| 7 | 0042952 | biological_process | beta-ketoadipate pathway |
| 8 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 8 | 0016853 | molecular_function | isomerase activity |
| 8 | 0042952 | biological_process | beta-ketoadipate pathway |
| 9 | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| 9 | 0016853 | molecular_function | isomerase activity |
| 9 | 0042952 | biological_process | beta-ketoadipate pathway |
| A | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0042952 | biological_process | beta-ketoadipate pathway |
| B | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0042952 | biological_process | beta-ketoadipate pathway |
| C | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0042952 | biological_process | beta-ketoadipate pathway |
| D | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0042952 | biological_process | beta-ketoadipate pathway |
| E | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0042952 | biological_process | beta-ketoadipate pathway |
| F | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0042952 | biological_process | beta-ketoadipate pathway |
| G | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0042952 | biological_process | beta-ketoadipate pathway |
| H | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0042952 | biological_process | beta-ketoadipate pathway |
| I | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| I | 0016853 | molecular_function | isomerase activity |
| I | 0042952 | biological_process | beta-ketoadipate pathway |
| J | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| J | 0016853 | molecular_function | isomerase activity |
| J | 0042952 | biological_process | beta-ketoadipate pathway |
| K | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| K | 0016853 | molecular_function | isomerase activity |
| K | 0042952 | biological_process | beta-ketoadipate pathway |
| L | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| L | 0016853 | molecular_function | isomerase activity |
| L | 0042952 | biological_process | beta-ketoadipate pathway |
| M | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| M | 0016853 | molecular_function | isomerase activity |
| M | 0042952 | biological_process | beta-ketoadipate pathway |
| N | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| N | 0016853 | molecular_function | isomerase activity |
| N | 0042952 | biological_process | beta-ketoadipate pathway |
| O | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| O | 0016853 | molecular_function | isomerase activity |
| O | 0042952 | biological_process | beta-ketoadipate pathway |
| P | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| P | 0016853 | molecular_function | isomerase activity |
| P | 0042952 | biological_process | beta-ketoadipate pathway |
| R | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| R | 0016853 | molecular_function | isomerase activity |
| R | 0042952 | biological_process | beta-ketoadipate pathway |
| S | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| S | 0016853 | molecular_function | isomerase activity |
| S | 0042952 | biological_process | beta-ketoadipate pathway |
| T | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| T | 0016853 | molecular_function | isomerase activity |
| T | 0042952 | biological_process | beta-ketoadipate pathway |
| U | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| U | 0016853 | molecular_function | isomerase activity |
| U | 0042952 | biological_process | beta-ketoadipate pathway |
| V | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| V | 0016853 | molecular_function | isomerase activity |
| V | 0042952 | biological_process | beta-ketoadipate pathway |
| W | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| W | 0016853 | molecular_function | isomerase activity |
| W | 0042952 | biological_process | beta-ketoadipate pathway |
| X | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| X | 0016853 | molecular_function | isomerase activity |
| X | 0042952 | biological_process | beta-ketoadipate pathway |
| Y | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| Y | 0016853 | molecular_function | isomerase activity |
| Y | 0042952 | biological_process | beta-ketoadipate pathway |
| Z | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| Z | 0016853 | molecular_function | isomerase activity |
| Z | 0042952 | biological_process | beta-ketoadipate pathway |
| a | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| a | 0016853 | molecular_function | isomerase activity |
| a | 0042952 | biological_process | beta-ketoadipate pathway |
| b | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| b | 0016853 | molecular_function | isomerase activity |
| b | 0042952 | biological_process | beta-ketoadipate pathway |
| c | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| c | 0016853 | molecular_function | isomerase activity |
| c | 0042952 | biological_process | beta-ketoadipate pathway |
| d | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| d | 0016853 | molecular_function | isomerase activity |
| d | 0042952 | biological_process | beta-ketoadipate pathway |
| e | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| e | 0016853 | molecular_function | isomerase activity |
| e | 0042952 | biological_process | beta-ketoadipate pathway |
| f | 0016159 | molecular_function | muconolactone delta-isomerase activity |
| f | 0016853 | molecular_function | isomerase activity |
| f | 0042952 | biological_process | beta-ketoadipate pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL 1 1095 |
| Chain | Residue |
| 1 | GLY51 |
| 1 | ASN52 |
| 1 | EDO1097 |
| Z | HIS87 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO 1 1096 |
| Chain | Residue |
| 1 | LEU4 |
| 1 | ARG6 |
| 1 | GLU82 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO 1 1097 |
| Chain | Residue |
| 1 | TRP40 |
| 1 | CL1095 |
| 1 | HOH2057 |
| Z | ALA89 |
| 1 | GLU27 |
| 1 | SER31 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL 2 1094 |
| Chain | Residue |
| 2 | GLY51 |
| 2 | ASN52 |
| 2 | EDO1096 |
| 3 | HIS87 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO 2 1095 |
| Chain | Residue |
| 2 | ARG6 |
| 2 | ASP80 |
| 2 | GLU82 |
| 2 | HOH2005 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO 2 1096 |
| Chain | Residue |
| 2 | GLU27 |
| 2 | SER31 |
| 2 | TRP40 |
| 2 | CL1094 |
| 2 | HOH2059 |
| 3 | HIS87 |
| 3 | ALA89 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL 3 1095 |
| Chain | Residue |
| 2 | HIS87 |
| 3 | ARG45 |
| 3 | ASN52 |
| 3 | EDO1096 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO 3 1096 |
| Chain | Residue |
| 2 | ALA89 |
| 3 | GLU27 |
| 3 | SER31 |
| 3 | CL1095 |
| 3 | HOH2068 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO 3 1097 |
| Chain | Residue |
| 2 | HOH2005 |
| 3 | LEU4 |
| 3 | ARG6 |
| 3 | GLU82 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL 4 1095 |
| Chain | Residue |
| 4 | ARG45 |
| 4 | GLY51 |
| 4 | ASN52 |
| 4 | EDO1097 |
| 5 | HIS87 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO 4 1096 |
| Chain | Residue |
| 4 | LEU4 |
| 4 | ARG6 |
| 4 | GLU82 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO 4 1097 |
| Chain | Residue |
| 4 | GLU27 |
| 4 | SER31 |
| 4 | TRP40 |
| 4 | CL1095 |
| 4 | HOH2038 |
| 5 | HIS87 |
| 5 | ALA89 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL 5 1093 |
| Chain | Residue |
| 4 | HIS87 |
| 5 | ASN52 |
| 5 | EDO1094 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO 5 1094 |
| Chain | Residue |
| 4 | HIS87 |
| 4 | ALA89 |
| 5 | GLU27 |
| 5 | SER31 |
| 5 | TRP40 |
| 5 | CL1093 |
| 5 | HOH2047 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO 5 1095 |
| Chain | Residue |
| 5 | LEU4 |
| 5 | ARG6 |
| 5 | ASP80 |
| 5 | GLU82 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL 6 1095 |
| Chain | Residue |
| 6 | ARG45 |
| 6 | ASN52 |
| 6 | EDO1096 |
| 7 | HIS87 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO 6 1096 |
| Chain | Residue |
| 6 | GLU27 |
| 6 | SER31 |
| 6 | TRP40 |
| 6 | CL1095 |
| 6 | HOH2046 |
| 7 | ALA89 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO 6 1097 |
| Chain | Residue |
| 6 | LEU4 |
| 6 | ARG6 |
| 6 | ASP80 |
| 6 | GLU82 |
| 7 | ARG6 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL 7 1093 |
| Chain | Residue |
| 6 | HIS87 |
| 7 | ARG45 |
| 7 | GLY51 |
| 7 | ASN52 |
| 7 | EDO1095 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO 7 1094 |
| Chain | Residue |
| 6 | ARG6 |
| 7 | LEU4 |
| 7 | ARG6 |
| 7 | ASP80 |
| 7 | GLU82 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO 7 1095 |
| Chain | Residue |
| 7 | CL1093 |
| 7 | HOH2041 |
| 6 | ALA89 |
| 7 | GLU27 |
| 7 | SER31 |
| 7 | TRP40 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL 8 1095 |
| Chain | Residue |
| 8 | ARG45 |
| 8 | ASN52 |
| 8 | EDO1097 |
| 9 | HIS87 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO 8 1096 |
| Chain | Residue |
| 8 | ARG6 |
| 8 | GLU82 |
| 8 | HOH2004 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO 8 1097 |
| Chain | Residue |
| 8 | GLU27 |
| 8 | SER31 |
| 8 | TRP40 |
| 8 | CL1095 |
| 8 | HOH2056 |
| 9 | HIS87 |
| 9 | ALA89 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL 9 1094 |
| Chain | Residue |
| 8 | HIS87 |
| 9 | ARG45 |
| 9 | GLY51 |
| 9 | ASN52 |
| 9 | EDO1096 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO 9 1095 |
| Chain | Residue |
| 8 | HOH2004 |
| 9 | LEU4 |
| 9 | ARG6 |
| 9 | GLU82 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO 9 1096 |
| Chain | Residue |
| 8 | ALA89 |
| 9 | GLU27 |
| 9 | SER31 |
| 9 | TRP40 |
| 9 | CL1094 |
| 9 | HOH2050 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1095 |
| Chain | Residue |
| A | ARG45 |
| A | ASN52 |
| A | EDO1097 |
| B | HIS87 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1096 |
| Chain | Residue |
| A | LEU4 |
| A | ARG6 |
| A | ASP80 |
| A | GLU82 |
| A | HOH2013 |
| A | HOH2015 |
| B | ARG6 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1097 |
| Chain | Residue |
| A | GLU27 |
| A | SER31 |
| A | TRP40 |
| A | CL1095 |
| A | HOH2154 |
| B | HIS87 |
| B | ALA89 |
| site_id | DC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1095 |
| Chain | Residue |
| A | HIS87 |
| B | GLY51 |
| B | ASN52 |
| B | EDO1097 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1096 |
| Chain | Residue |
| A | HOH2015 |
| B | ARG6 |
| B | GLU82 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1097 |
| Chain | Residue |
| A | HIS87 |
| A | ALA89 |
| B | GLU27 |
| B | SER31 |
| B | TRP40 |
| B | CL1095 |
| B | HOH2142 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 1095 |
| Chain | Residue |
| C | ARG45 |
| C | GLY51 |
| C | ASN52 |
| C | EDO1097 |
| D | HIS87 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 1096 |
| Chain | Residue |
| C | LEU4 |
| C | ARG6 |
| C | GLU82 |
| site_id | DC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1097 |
| Chain | Residue |
| C | GLU27 |
| C | SER31 |
| C | TRP40 |
| C | CL1095 |
| C | HOH2168 |
| D | HIS87 |
| D | ALA89 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1095 |
| Chain | Residue |
| C | HIS87 |
| D | ARG45 |
| D | ASN52 |
| D | EDO1097 |
| site_id | EC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1096 |
| Chain | Residue |
| C | HOH2016 |
| D | LEU4 |
| D | ARG6 |
| D | GLU82 |
| site_id | EC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1097 |
| Chain | Residue |
| C | ALA89 |
| D | GLU27 |
| D | SER31 |
| D | TRP40 |
| D | CL1095 |
| D | HOH2146 |
| site_id | EC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL E 1095 |
| Chain | Residue |
| E | ARG45 |
| E | GLY51 |
| E | ASN52 |
| E | EDO1097 |
| F | HIS87 |
| site_id | EC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO E 1096 |
| Chain | Residue |
| E | LEU4 |
| E | ARG6 |
| E | GLU82 |
| E | HOH2011 |
| E | HOH2159 |
| E | HOH2160 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO E 1097 |
| Chain | Residue |
| E | GLU27 |
| E | SER31 |
| E | TRP40 |
| E | CL1095 |
| E | HOH2161 |
| F | ALA89 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL F 1095 |
| Chain | Residue |
| E | HIS87 |
| F | ARG45 |
| F | ASN52 |
| F | EDO1097 |
| site_id | EC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO F 1096 |
| Chain | Residue |
| E | HOH2011 |
| F | LEU4 |
| F | ARG6 |
| F | GLU82 |
| site_id | EC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO F 1097 |
| Chain | Residue |
| E | ALA89 |
| F | GLU27 |
| F | SER31 |
| F | TRP40 |
| F | CL1095 |
| F | HOH2121 |
| site_id | FC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL G 1095 |
| Chain | Residue |
| G | ARG45 |
| G | ASN52 |
| G | EDO1096 |
| H | HIS87 |
| site_id | FC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO G 1096 |
| Chain | Residue |
| G | GLU27 |
| G | SER31 |
| G | TRP40 |
| G | CL1095 |
| G | HOH2137 |
| H | ALA89 |
| site_id | FC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 1097 |
| Chain | Residue |
| G | LEU4 |
| G | ARG6 |
| G | GLU82 |
| G | HOH2005 |
| G | HOH2138 |
| site_id | FC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL H 1095 |
| Chain | Residue |
| G | HIS87 |
| H | ARG45 |
| H | GLY51 |
| H | ASN52 |
| H | EDO1097 |
| site_id | FC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO H 1096 |
| Chain | Residue |
| G | HOH2138 |
| H | LEU4 |
| H | ARG6 |
| H | GLU82 |
| H | HOH2092 |
| site_id | FC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 1097 |
| Chain | Residue |
| G | ALA89 |
| H | GLU27 |
| H | SER31 |
| H | TRP40 |
| H | CL1095 |
| H | HOH2093 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL I 1095 |
| Chain | Residue |
| I | ARG45 |
| I | GLY51 |
| I | ASN52 |
| I | EDO1097 |
| J | HIS87 |
| site_id | FC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO I 1096 |
| Chain | Residue |
| I | ARG6 |
| I | ASP80 |
| I | GLU82 |
| site_id | FC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO I 1097 |
| Chain | Residue |
| I | GLU27 |
| I | SER31 |
| I | TRP40 |
| I | CL1095 |
| I | HOH2075 |
| J | HIS87 |
| J | ALA89 |
| site_id | GC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL J 1095 |
| Chain | Residue |
| I | HIS87 |
| J | ARG45 |
| J | ASN52 |
| J | EDO1097 |
| J | HOH2056 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO J 1096 |
| Chain | Residue |
| I | HOH2006 |
| J | LEU4 |
| J | ARG6 |
| J | ASP80 |
| J | GLU82 |
| site_id | GC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO J 1097 |
| Chain | Residue |
| I | HIS87 |
| I | ALA89 |
| J | GLU27 |
| J | SER31 |
| J | TRP40 |
| J | CL1095 |
| J | HOH2090 |
| site_id | GC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL K 1095 |
| Chain | Residue |
| K | GLY51 |
| K | ASN52 |
| K | EDO1097 |
| L | HIS87 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO K 1096 |
| Chain | Residue |
| K | LEU4 |
| K | ARG6 |
| K | GLU82 |
| K | HOH2007 |
| site_id | GC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO K 1097 |
| Chain | Residue |
| K | GLU27 |
| K | SER31 |
| K | TRP40 |
| K | CL1095 |
| K | HOH2103 |
| L | HIS87 |
| L | ALA89 |
| site_id | GC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL L 1095 |
| Chain | Residue |
| K | HIS87 |
| L | ARG45 |
| L | ASN52 |
| L | EDO1097 |
| site_id | GC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO L 1096 |
| Chain | Residue |
| K | HOH2007 |
| L | ARG6 |
| L | GLU82 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO L 1097 |
| Chain | Residue |
| K | ALA89 |
| L | GLU27 |
| L | SER31 |
| L | CL1095 |
| L | HOH2087 |
| site_id | HC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL M 1095 |
| Chain | Residue |
| M | ARG45 |
| M | ASN52 |
| M | EDO1097 |
| N | HIS87 |
| site_id | HC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO M 1096 |
| Chain | Residue |
| M | LEU4 |
| M | ARG6 |
| M | ASP80 |
| M | GLU82 |
| M | HOH2008 |
| M | HOH2073 |
| site_id | HC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO M 1097 |
| Chain | Residue |
| M | GLU27 |
| M | SER31 |
| M | TRP40 |
| M | CL1095 |
| M | HOH2084 |
| N | ALA89 |
| site_id | HC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL N 1095 |
| Chain | Residue |
| M | HIS87 |
| N | ARG45 |
| N | ASN52 |
| N | EDO1097 |
| site_id | HC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO N 1096 |
| Chain | Residue |
| N | LEU4 |
| N | ARG6 |
| N | ASP80 |
| N | GLU82 |
| N | HOH2072 |
| N | HOH2077 |
| site_id | HC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO N 1097 |
| Chain | Residue |
| M | ALA89 |
| N | GLU27 |
| N | SER31 |
| N | TRP40 |
| N | CL1095 |
| N | HOH2078 |
| site_id | HC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL O 1095 |
| Chain | Residue |
| O | ASN52 |
| O | EDO1096 |
| P | HIS87 |
| site_id | HC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO O 1096 |
| Chain | Residue |
| O | GLU27 |
| O | SER31 |
| O | TRP40 |
| O | CL1095 |
| O | HOH2064 |
| site_id | HC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO O 1097 |
| Chain | Residue |
| O | ARG6 |
| O | GLU82 |
| O | HOH2006 |
| site_id | IC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL P 1095 |
| Chain | Residue |
| O | HIS87 |
| P | GLY51 |
| P | ASN52 |
| P | EDO1096 |
| site_id | IC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO P 1096 |
| Chain | Residue |
| O | HIS87 |
| O | ALA89 |
| P | GLU27 |
| P | SER31 |
| P | TRP40 |
| P | CL1095 |
| P | HOH2067 |
| site_id | IC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO P 1097 |
| Chain | Residue |
| O | HOH2006 |
| P | LEU4 |
| P | ARG6 |
| P | GLU82 |
| site_id | IC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL R 1095 |
| Chain | Residue |
| R | ARG45 |
| R | ASN52 |
| R | EDO1097 |
| R | HOH2061 |
| S | HIS87 |
| site_id | IC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO R 1096 |
| Chain | Residue |
| R | ARG6 |
| R | GLU82 |
| R | HOH2079 |
| R | HOH2094 |
| site_id | IC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO R 1097 |
| Chain | Residue |
| R | GLU27 |
| R | SER31 |
| R | TRP40 |
| R | CL1095 |
| R | HOH2095 |
| S | HIS87 |
| S | ALA89 |
| site_id | IC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL S 1095 |
| Chain | Residue |
| R | HIS87 |
| S | ARG45 |
| S | ASN52 |
| S | EDO1097 |
| site_id | IC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO S 1096 |
| Chain | Residue |
| R | HOH2010 |
| S | LEU4 |
| S | ARG6 |
| S | GLU82 |
| S | HOH2082 |
| site_id | IC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO S 1097 |
| Chain | Residue |
| R | HIS87 |
| R | ALA89 |
| S | GLU27 |
| S | SER31 |
| S | TRP40 |
| S | CL1095 |
| S | HOH2088 |
| site_id | JC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL T 1095 |
| Chain | Residue |
| T | ARG45 |
| T | ASN52 |
| T | EDO1096 |
| U | HIS87 |
| site_id | JC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO T 1096 |
| Chain | Residue |
| T | GLU27 |
| T | SER31 |
| T | TRP40 |
| T | CL1095 |
| T | HOH2082 |
| U | ALA89 |
| site_id | JC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO T 1097 |
| Chain | Residue |
| T | LEU4 |
| T | ARG6 |
| T | GLU82 |
| T | HOH2004 |
| T | HOH2006 |
| site_id | JC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL U 1095 |
| Chain | Residue |
| T | HIS87 |
| U | ARG45 |
| U | GLY51 |
| U | ASN52 |
| U | EDO1096 |
| site_id | JC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO U 1096 |
| Chain | Residue |
| T | ALA89 |
| U | GLU27 |
| U | SER31 |
| U | TRP40 |
| U | CL1095 |
| U | HOH2054 |
| site_id | JC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL V 1095 |
| Chain | Residue |
| V | ARG45 |
| V | ASN52 |
| W | HIS87 |
| site_id | JC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO V 1096 |
| Chain | Residue |
| V | LEU4 |
| V | ARG6 |
| V | GLU82 |
| V | HOH2005 |
| site_id | JC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO V 1097 |
| Chain | Residue |
| V | GLU27 |
| V | SER31 |
| V | TRP40 |
| W | HIS87 |
| W | ALA89 |
| site_id | JC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL W 1095 |
| Chain | Residue |
| V | HIS87 |
| W | ARG45 |
| W | GLY51 |
| W | ASN52 |
| W | EDO1097 |
| site_id | KC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO W 1096 |
| Chain | Residue |
| V | HOH2005 |
| W | LEU4 |
| W | ARG6 |
| W | ASP80 |
| W | GLU82 |
| site_id | KC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO W 1097 |
| Chain | Residue |
| V | ALA89 |
| W | GLU27 |
| W | SER31 |
| W | CL1095 |
| site_id | KC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL X 1095 |
| Chain | Residue |
| X | ARG45 |
| X | ASN52 |
| X | EDO1097 |
| Y | HIS87 |
| site_id | KC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO X 1096 |
| Chain | Residue |
| X | ARG6 |
| X | GLU82 |
| site_id | KC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO X 1097 |
| Chain | Residue |
| X | GLU27 |
| X | SER31 |
| X | TRP40 |
| X | CL1095 |
| X | HOH2042 |
| Y | ALA89 |
| site_id | KC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL Y 1092 |
| Chain | Residue |
| X | HIS87 |
| Y | ARG45 |
| Y | ASN52 |
| Y | EDO1094 |
| site_id | KC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO Y 1093 |
| Chain | Residue |
| Y | LEU4 |
| Y | ARG6 |
| Y | ASP80 |
| Y | GLU82 |
| site_id | KC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO Y 1094 |
| Chain | Residue |
| X | HIS87 |
| X | ALA89 |
| Y | GLU27 |
| Y | SER31 |
| Y | TRP40 |
| Y | CL1092 |
| Y | HOH2029 |
| site_id | KC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL Z 1095 |
| Chain | Residue |
| 1 | HIS87 |
| Z | ARG45 |
| Z | ASN52 |
| Z | EDO1096 |
| site_id | LC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO Z 1096 |
| Chain | Residue |
| Z | GLU27 |
| Z | SER31 |
| Z | TRP40 |
| Z | CL1095 |
| Z | HOH2044 |
| site_id | LC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL a 1095 |
| Chain | Residue |
| a | GLY51 |
| a | ASN52 |
| a | EDO1097 |
| b | HIS87 |
| site_id | LC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO a 1096 |
| Chain | Residue |
| a | LEU4 |
| a | ARG6 |
| a | ASP80 |
| a | GLU82 |
| site_id | LC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO a 1097 |
| Chain | Residue |
| A | HOH2155 |
| a | GLU27 |
| a | SER31 |
| a | TRP40 |
| a | CL1095 |
| b | HIS87 |
| b | ALA89 |
| site_id | LC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL b 1095 |
| Chain | Residue |
| a | HIS87 |
| b | ARG45 |
| b | ASN52 |
| b | EDO1097 |
| site_id | LC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO b 1096 |
| Chain | Residue |
| A | HOH2018 |
| b | LEU4 |
| b | ARG6 |
| b | GLU82 |
| site_id | LC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO b 1097 |
| Chain | Residue |
| B | HOH2143 |
| a | HIS87 |
| a | ALA89 |
| b | GLU27 |
| b | SER31 |
| b | TRP40 |
| b | CL1095 |
| site_id | LC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL c 1095 |
| Chain | Residue |
| C | HOH2100 |
| c | ARG45 |
| c | ASN52 |
| c | EDO1097 |
| d | HIS87 |
| site_id | LC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO c 1096 |
| Chain | Residue |
| C | HOH2019 |
| c | LEU4 |
| c | ARG6 |
| c | ASP80 |
| c | GLU82 |
| site_id | MC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO c 1097 |
| Chain | Residue |
| C | HOH2169 |
| c | GLU27 |
| c | SER31 |
| c | TRP40 |
| c | CL1095 |
| d | HIS87 |
| d | ALA89 |
| site_id | MC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL d 1095 |
| Chain | Residue |
| c | HIS87 |
| d | ARG45 |
| d | ASN52 |
| d | EDO1097 |
| site_id | MC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO d 1096 |
| Chain | Residue |
| C | HOH2019 |
| d | LEU4 |
| d | ARG6 |
| d | ASP80 |
| d | GLU82 |
| site_id | MC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO d 1097 |
| Chain | Residue |
| D | HOH2147 |
| c | HIS87 |
| c | ALA89 |
| d | GLU27 |
| d | SER31 |
| d | TRP40 |
| d | CL1095 |
| site_id | MC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL e 1093 |
| Chain | Residue |
| e | ASN52 |
| e | EDO1095 |
| f | HIS87 |
| site_id | MC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO e 1094 |
| Chain | Residue |
| E | HOH2157 |
| e | LEU4 |
| e | ARG6 |
| e | ASP80 |
| e | GLU82 |
| site_id | MC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO e 1095 |
| Chain | Residue |
| E | HOH2158 |
| e | GLU27 |
| e | SER31 |
| e | TRP40 |
| e | CL1093 |
| f | ALA89 |
| site_id | MC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL f 1095 |
| Chain | Residue |
| e | HIS87 |
| f | ARG45 |
| f | ASN52 |
| f | EDO1097 |
| site_id | MC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO f 1096 |
| Chain | Residue |
| E | HOH2014 |
| f | LEU4 |
| f | ARG6 |
| f | GLU82 |
| site_id | NC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO f 1097 |
| Chain | Residue |
| F | HOH2122 |
| e | HIS87 |
| e | ALA89 |
| f | GLU27 |
| f | SER31 |
| f | TRP40 |
| f | CL1095 |
