3ZMK

Anopheles funestus glutathione-s-transferase epsilon 2 (GSTe2) protein structure from different alelles: A single amino acid change confers high level of DDT resistance and cross resistance to permethrin in a major malaria vector in Africa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004364	molecular_function	glutathione transferase activity
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity
B	0003824	molecular_function	catalytic activity
B	0004364	molecular_function	glutathione transferase activity
B	0006749	biological_process	glutathione metabolic process
B	0016740	molecular_function	transferase activity
C	0003824	molecular_function	catalytic activity
C	0004364	molecular_function	glutathione transferase activity
C	0006749	biological_process	glutathione metabolic process
C	0016740	molecular_function	transferase activity
D	0003824	molecular_function	catalytic activity
D	0004364	molecular_function	glutathione transferase activity
D	0006749	biological_process	glutathione metabolic process
D	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GSH B 1221

Chain	Residue
B	SER12
B	PRO14
B	LEU36
B	THR54
B	ILE55
B	GLU67
B	SER68
B	HIS69
B	ARG112

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site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GSH D 1222

Chain	Residue
D	SER12
D	PRO14
D	THR54
D	ILE55
D	PRO56
D	GLU67
D	SER68
D	ARG112
D	HOH2020
D	HOH2039
D	HOH2074
D	HOH2075
D	HOH2076

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