3ZHG

Crystallographic structure of the native mouse SIGN-R1 CRD domain

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 501

Chain	Residue
A	GLU296
A	SER305
A	LEU309
A	LYS311
A	HOH2123
A	HOH2125
A	HOH2126

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 502

Chain	Residue
A	HOH2024
A	HOH2044
A	HOH2051
A	LYS317
A	SER318

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 503

Chain	Residue
A	ASN205
A	ASN234
A	LYS316
A	HOH2054

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 504

Chain	Residue
A	ASP236
A	ARG276
A	HOH2056

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 505

Chain	Residue
A	ARG276
A	ASN288
A	ILE289

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 506

Chain	Residue
A	LYS211
A	LYS249
A	HOH2012
A	HOH2138
B	ARG193
B	LEU194
B	CYS195

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 501

Chain	Residue
B	GLU296
B	SER305
B	LEU309
B	LYS311
B	HOH2061
B	HOH2062

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 503

Chain	Residue
B	ASN205
B	ASN234
B	LYS316
B	HOH2033
D	HOH2072

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 504

Chain	Residue
B	ASN234
B	SER235
B	ASP236
B	ARG276
B	HOH2034

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 501

Chain	Residue
C	GLU296
C	SER305
C	LEU309
C	LYS311
C	HOH2110
C	HOH2126

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 502

Chain	Residue
C	LYS317
C	SER318
C	HOH2037
C	HOH2042
C	HOH2127

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 503

Chain	Residue
C	ASN205
C	ASN234
C	LYS316

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 504

Chain	Residue
C	SER235
C	ASP236
C	ARG276
C	HOH2047

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 505

Chain	Residue
C	ARG276
C	ASN288
C	ILE289

---

site_id	BC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 C 506

Chain	Residue
C	LYS211
C	LYS249
C	HOH2010
C	HOH2128
C	HOH2129
D	ARG193
D	LEU194
D	CYS195

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 501

Chain	Residue
D	GLU296
D	SER305
D	LEU309
D	LYS311
D	HOH2064

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 503

Chain	Residue
D	ASN205
D	ASN234
D	LYS316
D	HOH2072

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 504

Chain	Residue
D	ASN234
D	SER235
D	ASP236
D	ARG276
D	HOH2035

---

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1323

Chain	Residue
A	GLU285
A	ASN287
A	GLU292
A	ASP304
A	HOH2116
A	HOH2117

---

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA B 1323

Chain	Residue
B	GLU285
B	ASN287
B	GLU292
B	ASP304

---

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 1323

Chain	Residue
C	ASN287
C	GLU292
C	ASP304
C	HOH2104
C	GLU285

---

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 1323

Chain	Residue
D	GLU285
D	ASN287
D	GLU292
D	ASP304
D	HOH2060

---

Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	22
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVefagdg......WNDSKCelkkf.WIC

Chain	Residue	Details
D	CYS294-CYS315
A	CYS294-CYS315

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	460
Details	Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---