3ZHB
R-imine reductase from Streptomyces kanamyceticus in complex with NADP.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016020 | cellular_component | membrane |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0050661 | molecular_function | NADP binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016020 | cellular_component | membrane |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NAP A 1307 |
| Chain | Residue |
| A | LEU27 |
| A | VAL83 |
| A | SER84 |
| A | ALA88 |
| A | LEU92 |
| A | SER111 |
| A | ILE136 |
| A | ALA138 |
| A | PRO140 |
| A | HOH2001 |
| A | GLY28 |
| A | LEU29 |
| A | MET30 |
| A | ASN49 |
| A | ARG50 |
| A | THR51 |
| A | LYS54 |
| A | CYS82 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NAP D 1307 |
| Chain | Residue |
| D | LEU27 |
| D | GLY28 |
| D | LEU29 |
| D | MET30 |
| D | ASN49 |
| D | ARG50 |
| D | THR51 |
| D | LYS54 |
| D | CYS82 |
| D | VAL83 |
| D | SER84 |
| D | ALA88 |
| D | LEU92 |
| D | SER111 |
| D | ILE136 |
| D | ALA138 |
| D | PRO140 |
| D | HOH2004 |
| D | HOH2008 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NAP C 1307 |
| Chain | Residue |
| C | LEU27 |
| C | GLY28 |
| C | LEU29 |
| C | MET30 |
| C | ASN49 |
| C | ARG50 |
| C | THR51 |
| C | LYS54 |
| C | CYS82 |
| C | VAL83 |
| C | SER84 |
| C | ALA88 |
| C | LEU92 |
| C | SER111 |
| C | ILE136 |
| C | ALA138 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NAP B 1307 |
| Chain | Residue |
| B | GLY26 |
| B | LEU27 |
| B | GLY28 |
| B | MET30 |
| B | ASN49 |
| B | ARG50 |
| B | THR51 |
| B | CYS82 |
| B | VAL83 |
| B | SER84 |
| B | ALA88 |
| B | SER111 |
| B | ILE136 |
| B | ALA138 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 30 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGLGLMGQALaGaflgaghpttvwnr....TAAK |
| Chain | Residue | Details |
| A | ILE25-LYS54 |
