3ZH4

crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008360	biological_process	regulation of cell shape
A	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FLC A 1419

Chain	Residue
A	LYS22
A	ARG398
A	HOH2030
A	HOH2099
A	HOH2100
A	HOH2298
A	HOH2336
A	ASN23
A	ARG92
A	LEU118
A	ASP306
A	ARG332
A	ASP370
A	LEU371
A	ARG372

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PEG A 1420

Chain	Residue
A	ARG92
A	SER164
A	VAL165
A	GLY166
A	TYR329
A	HOH2102
A	HOH2348

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00111

Chain	Residue	Details
A	CYS116

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0A749

Chain	Residue	Details
A	ARG121
A	ASP306
A	ILE328
A	LYS22
A	ARG92

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: 2-(S-cysteinyl)pyruvic acid O-phosphothioketal => ECO:0000255|HAMAP-Rule:MF_00111

Chain	Residue	Details
A	CYS116

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