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3X29

CRYSTAL STRUCTURE of MOUSE CLAUDIN-19 IN COMPLEX with C-TERMINAL FRAGMENT OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN

Functional Information from GO Data
ChainGOidnamespacecontents
A0005198molecular_functionstructural molecule activity
A0005923cellular_componentbicellular tight junction
A0016020cellular_componentmembrane
B0005576cellular_componentextracellular region
C0005198molecular_functionstructural molecule activity
C0005923cellular_componentbicellular tight junction
C0016020cellular_componentmembrane
D0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS01346
Number of Residues16
DetailsCLAUDIN Claudin family signature. GLWmsCasqstgqv.QC
ChainResidueDetails
AGLY49-CYS64

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
AMET1-GLN7
ALYS103-ARG117
CMET1-GLN7
CLYS103-ARG117

site_idSWS_FT_FI2
Number of Residues160
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
ALEU8-PRO28
AALA82-MET102
AVAL118-SER138
APHE161-PHE181
CLEU8-PRO28
CALA82-MET102
CVAL118-SER138
CPHE161-PHE181

site_idSWS_FT_FI3
Number of Residues146
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
AGLN29-ARG81
ATRP139-GLU160
CGLN29-ARG81
CTRP139-GLU160

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PDB entries from 2024-10-30

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