3X1K
crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with AMP-PNP from Pseudomonas aerugonosa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0015937 | biological_process | coenzyme A biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0015937 | biological_process | coenzyme A biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0015937 | biological_process | coenzyme A biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| E | 0009058 | biological_process | biosynthetic process |
| E | 0015937 | biological_process | coenzyme A biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016779 | molecular_function | nucleotidyltransferase activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| F | 0009058 | biological_process | biosynthetic process |
| F | 0015937 | biological_process | coenzyme A biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ANP A 1001 |
| Chain | Residue |
| A | TYR6 |
| A | GLY88 |
| A | ARG90 |
| A | ASP94 |
| A | GLU98 |
| A | PRO119 |
| A | TYR123 |
| A | ILE126 |
| A | SER127 |
| A | SER128 |
| A | THR129 |
| A | GLY8 |
| A | HOH1105 |
| A | HOH1107 |
| A | THR9 |
| A | PHE10 |
| A | GLY16 |
| A | HIS17 |
| A | LEU20 |
| A | LYS41 |
| A | ARG87 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 1002 |
| Chain | Residue |
| A | ARG26 |
| A | LEU27 |
| C | ASN83 |
| C | ASP111 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 1003 |
| Chain | Residue |
| A | ARG156 |
| A | LYS158 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1004 |
| Chain | Residue |
| A | PRO110 |
| A | VAL112 |
| A | GLU113 |
| C | ARG23 |
| C | ARG26 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 1005 |
| Chain | Residue |
| A | ASN83 |
| A | ASP111 |
| C | ARG26 |
| C | LEU27 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ANP B 1001 |
| Chain | Residue |
| B | TYR6 |
| B | THR9 |
| B | PHE10 |
| B | GLY16 |
| B | HIS17 |
| B | LEU20 |
| B | LYS41 |
| B | ARG87 |
| B | GLY88 |
| B | ARG90 |
| B | ASP94 |
| B | GLU98 |
| B | PRO119 |
| B | TYR123 |
| B | ILE126 |
| B | SER127 |
| B | SER128 |
| B | THR129 |
| B | HOH1102 |
| B | HOH1103 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS B 1002 |
| Chain | Residue |
| B | ALA36 |
| B | ALA37 |
| B | SER38 |
| B | PRO39 |
| B | PHE69 |
| B | THR71 |
| B | HOH1122 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS B 1003 |
| Chain | Residue |
| B | GLY8 |
| B | ALA36 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS B 1004 |
| Chain | Residue |
| B | ASN83 |
| B | ASP111 |
| D | LEU27 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B 1005 |
| Chain | Residue |
| B | ARG156 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B 1006 |
| Chain | Residue |
| B | ARG156 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 1007 |
| Chain | Residue |
| B | THR58 |
| B | LYS59 |
| B | LEU61 |
| B | VAL64 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT B 1008 |
| Chain | Residue |
| B | SER70 |
| B | THR71 |
| site_id | BC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ANP C 1001 |
| Chain | Residue |
| C | TYR6 |
| C | THR9 |
| C | PHE10 |
| C | GLY16 |
| C | HIS17 |
| C | LEU20 |
| C | LYS41 |
| C | ARG87 |
| C | GLY88 |
| C | ARG90 |
| C | ASP94 |
| C | GLU98 |
| C | PRO119 |
| C | TYR123 |
| C | ILE126 |
| C | SER127 |
| C | SER128 |
| C | THR129 |
| C | HOH1102 |
| C | HOH1110 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS C 1002 |
| Chain | Residue |
| C | GLU22 |
| C | TYR123 |
| C | LYS15 |
| C | GLY18 |
| C | ASP19 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PO4 C 1003 |
| Chain | Residue |
| C | LEU130 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 1004 |
| Chain | Residue |
| C | PRO7 |
| C | GLY8 |
| C | ALA36 |
| C | ARG87 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL C 1005 |
| Chain | Residue |
| C | ASP29 |
| site_id | CC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ANP D 1001 |
| Chain | Residue |
| D | TYR6 |
| D | THR9 |
| D | PHE10 |
| D | GLY16 |
| D | HIS17 |
| D | LEU20 |
| D | LYS41 |
| D | ARG87 |
| D | GLY88 |
| D | ARG90 |
| D | ASP94 |
| D | GLU98 |
| D | PRO119 |
| D | TYR123 |
| D | ILE126 |
| D | SER127 |
| D | SER128 |
| D | THR129 |
| D | HOH1108 |
| D | HOH1110 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS D 1002 |
| Chain | Residue |
| D | GLY8 |
| D | ALA36 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS D 1003 |
| Chain | Residue |
| D | LYS15 |
| D | GLY18 |
| D | ASP19 |
| D | GLU22 |
| D | TYR123 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT D 1004 |
| Chain | Residue |
| D | SER93 |
| site_id | CC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ANP E 1001 |
| Chain | Residue |
| E | TYR6 |
| E | GLY8 |
| E | THR9 |
| E | PHE10 |
| E | GLY16 |
| E | HIS17 |
| E | LEU20 |
| E | ARG87 |
| E | GLY88 |
| E | ARG90 |
| E | GLU98 |
| E | PRO119 |
| E | TYR123 |
| E | ILE126 |
| E | SER127 |
| E | SER128 |
| E | THR129 |
| E | HOH1112 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS E 1002 |
| Chain | Residue |
| A | GLU133 |
| E | LEU73 |
| E | LEU101 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS E 1003 |
| Chain | Residue |
| E | ARG26 |
| E | LEU27 |
| F | ASN83 |
| F | ASP111 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS E 1004 |
| Chain | Residue |
| E | LYS15 |
| E | GLY18 |
| E | ASP19 |
| E | GLU22 |
| E | TYR123 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS E 1005 |
| Chain | Residue |
| E | PHE69 |
| E | SER70 |
| E | THR71 |
| site_id | DC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMS E 1006 |
| Chain | Residue |
| E | ARG87 |
| site_id | DC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ANP F 1001 |
| Chain | Residue |
| F | TYR6 |
| F | GLY8 |
| F | THR9 |
| F | PHE10 |
| F | GLY16 |
| F | HIS17 |
| F | LEU20 |
| F | ARG87 |
| F | GLY88 |
| F | ARG90 |
| F | GLU98 |
| F | PRO119 |
| F | TYR123 |
| F | ILE126 |
| F | SER127 |
| F | SER128 |
| F | THR129 |
| site_id | DC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS F 1002 |
| Chain | Residue |
| F | LEU130 |
| F | ILE134 |
| site_id | DC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS F 1003 |
| Chain | Residue |
| F | LEU72 |
| F | LEU101 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS F 1004 |
| Chain | Residue |
| F | LYS15 |
| F | GLY18 |
| F | ASP19 |
| F | TYR123 |
| F | HIS146 |
