3X1J
Crystal Structure of Phosphopantetheine adenylyltransferase (PPAT/CoaD) with AcCoA from Pseudomonas aeruginosa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0015937 | biological_process | coenzyme A biosynthetic process |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008771 | molecular_function | [citrate (pro-3S)-lyase] ligase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0015937 | biological_process | coenzyme A biosynthetic process |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ACO A 201 |
| Chain | Residue |
| A | TYR6 |
| A | ARG87 |
| A | GLY88 |
| A | ARG90 |
| A | TYR97 |
| A | LEU101 |
| A | ASN105 |
| A | SER127 |
| A | SER128 |
| A | THR129 |
| A | DMS207 |
| A | PRO7 |
| A | HOH303 |
| C | LEU130 |
| C | ILE134 |
| C | LEU137 |
| A | GLY8 |
| A | THR9 |
| A | HIS17 |
| A | ALA36 |
| A | LYS41 |
| A | LEU72 |
| A | LEU73 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 202 |
| Chain | Residue |
| A | GLY68 |
| A | PHE69 |
| A | SER70 |
| A | THR71 |
| A | PHE76 |
| A | GOL204 |
| A | HOH319 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 203 |
| Chain | Residue |
| A | ASN83 |
| A | ASP111 |
| C | ARG26 |
| C | LEU27 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 204 |
| Chain | Residue |
| A | LEU47 |
| A | GLY68 |
| A | PHE69 |
| A | SER70 |
| A | PO4202 |
| A | GOL205 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 205 |
| Chain | Residue |
| A | GOL204 |
| C | HIS75 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 206 |
| Chain | Residue |
| A | GLU48 |
| A | GLN49 |
| C | LEU47 |
| C | GLY68 |
| C | PHE69 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 207 |
| Chain | Residue |
| A | ALA37 |
| A | SER38 |
| A | PRO39 |
| A | PHE69 |
| A | SER70 |
| A | THR71 |
| A | ACO201 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 208 |
| Chain | Residue |
| A | LYS15 |
| A | GLY18 |
| A | ASP19 |
| A | TYR123 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 209 |
| Chain | Residue |
| A | GLU155 |
| A | ARG156 |
| A | LYS158 |
| C | GLN55 |
| C | GLU65 |
| C | VAL66 |
| C | HOH308 |
| site_id | BC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ACO B 201 |
| Chain | Residue |
| A | GLU133 |
| A | LEU137 |
| B | TYR6 |
| B | PRO7 |
| B | GLY8 |
| B | THR9 |
| B | HIS17 |
| B | ALA36 |
| B | LYS41 |
| B | PHE69 |
| B | THR71 |
| B | LEU72 |
| B | LEU73 |
| B | ARG87 |
| B | GLY88 |
| B | ARG90 |
| B | TYR97 |
| B | ASN105 |
| B | SER127 |
| B | SER128 |
| B | THR129 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS B 202 |
| Chain | Residue |
| B | LYS15 |
| B | GLY18 |
| B | ASP19 |
| B | GLU22 |
| B | TYR123 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS B 203 |
| Chain | Residue |
| B | ARG26 |
| B | LEU27 |
| B | ASN83 |
| B | ASP111 |
| B | HOH305 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 204 |
| Chain | Residue |
| B | GLU79 |
| B | GLY68 |
| B | SER70 |
| B | THR71 |
| site_id | BC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ACO C 201 |
| Chain | Residue |
| B | LEU130 |
| B | GLU133 |
| B | ILE134 |
| C | TYR6 |
| C | PRO7 |
| C | GLY8 |
| C | THR9 |
| C | HIS17 |
| C | LYS41 |
| C | PHE69 |
| C | THR71 |
| C | LEU73 |
| C | ARG87 |
| C | ARG90 |
| C | TYR97 |
| C | LEU101 |
| C | ASN105 |
| C | SER127 |
| C | SER128 |
| C | THR129 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS C 202 |
| Chain | Residue |
| C | LYS15 |
| C | GLY18 |
| C | ASP19 |
| C | GLU22 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS C 203 |
| Chain | Residue |
| A | PRO39 |
| C | GLU133 |
