Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0009098 | biological_process | L-leucine biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0046872 | molecular_function | metal ion binding |
A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE IPM A 401 |
Chain | Residue |
A | GLU89 |
A | HOH579 |
A | HOH685 |
A | HOH686 |
A | HOH700 |
A | ARG97 |
A | ARG107 |
A | ARG136 |
A | TYR143 |
A | LYS193 |
A | ASP225 |
A | ASP249 |
A | MG402 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG A 402 |
Chain | Residue |
A | ASP225 |
A | ASP249 |
A | IPM401 |
A | HOH685 |
A | HOH700 |
Functional Information from PROSITE/UniProt
site_id | PS00470 |
Number of Residues | 20 |
Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLFGDIlSDeiAmlt.GSMGL |
Chain | Residue | Details |
A | ASN245-LEU264 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLY76 | |
A | ARG97 | |
A | ARG107 | |
A | ARG136 | |
A | ASP225 | |
A | ASP249 | |
A | ASP253 | |
A | GLY283 | |
Chain | Residue | Details |
A | TYR143 | |
A | LYS193 | |