Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE IPM A 401 |
| Chain | Residue |
| A | GLU89 |
| A | ASP249 |
| A | MG402 |
| A | HOH522 |
| A | HOH639 |
| A | HOH736 |
| A | ARG97 |
| A | ARG107 |
| A | ARG136 |
| A | TYR143 |
| A | LYS193 |
| A | ASN195 |
| A | VAL196 |
| A | ASP225 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP225 |
| A | ASP249 |
| A | IPM401 |
| A | HOH522 |
| A | HOH736 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLFGDIlSDeiAmlt.GSMGL |
| Chain | Residue | Details |
| A | ASN245-LEU264 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ARG107 | |
| A | ARG136 | |
| A | ASP225 | |
| A | ASP249 | |
| A | ASP253 | |
| A | GLY283 | |
| A | GLY76 | |
| A | ARG97 | |
| Chain | Residue | Details |
| A | TYR143 | |
| A | LYS193 | |
