Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 401 |
| Chain | Residue |
| A | SER233 |
| A | ALA237 |
| A | TYR251 |
| A | HOH535 |
| A | HOH536 |
| A | HOH537 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 402 |
| Chain | Residue |
| A | HOH508 |
| A | HOH511 |
| A | GLN140 |
| A | GLN141 |
| A | LYS142 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 403 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | PRO282 |
| A | CYS290 |
| A | HOH803 |
| A | HOH805 |
| A | HOH1046 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 404 |
| Chain | Residue |
| A | ASP15 |
| A | ILE283 |
| A | HOH740 |
| A | HOH1001 |
| A | HOH1093 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 A 405 |
| Chain | Residue |
| A | ALA187 |
| A | SER189 |
| A | GLU196 |
| A | TRP197 |
| A | THR198 |
| A | ASP215 |
| A | HOH566 |
| A | HOH568 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG6 A 406 |
| Chain | Residue |
| A | THR168 |
| A | PHE173 |
| A | ASP175 |
| A | HOH617 |
| A | HOH1019 |
| A | HOH1020 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG A 407 |
| Chain | Residue |
| A | VAL272 |
| A | TYR277 |
| A | LYS330 |
| A | HOH712 |
| A | HOH845 |
| A | HOH909 |
| A | HOH938 |
| A | HOH957 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 408 |
| Chain | Residue |
| A | ILE10 |
| A | ASP15 |
| A | HOH981 |
| A | HOH1105 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE IXZ A 409 |
| Chain | Residue |
| A | ASP33 |
| A | ASP35 |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | PHE116 |
| A | ASP219 |
| A | GLY221 |
| A | THR222 |
| A | TYR226 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
