3WXJ

Crystal structure of trypanosoma brucei gambiense glycerol kinase in complex with glycerol 3-phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004370	molecular_function	glycerol kinase activity
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005975	biological_process	carbohydrate metabolic process
A	0006071	biological_process	glycerol metabolic process
A	0006072	biological_process	glycerol-3-phosphate metabolic process
A	0006641	biological_process	triglyceride metabolic process
A	0016301	molecular_function	kinase activity
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0019563	biological_process	glycerol catabolic process
A	0046167	biological_process	glycerol-3-phosphate biosynthetic process
B	0004370	molecular_function	glycerol kinase activity
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005975	biological_process	carbohydrate metabolic process
B	0006071	biological_process	glycerol metabolic process
B	0006072	biological_process	glycerol-3-phosphate metabolic process
B	0006641	biological_process	triglyceride metabolic process
B	0016301	molecular_function	kinase activity
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0019563	biological_process	glycerol catabolic process
B	0046167	biological_process	glycerol-3-phosphate biosynthetic process
C	0004370	molecular_function	glycerol kinase activity
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005975	biological_process	carbohydrate metabolic process
C	0006071	biological_process	glycerol metabolic process
C	0006072	biological_process	glycerol-3-phosphate metabolic process
C	0006641	biological_process	triglyceride metabolic process
C	0016301	molecular_function	kinase activity
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0019563	biological_process	glycerol catabolic process
C	0046167	biological_process	glycerol-3-phosphate biosynthetic process
D	0004370	molecular_function	glycerol kinase activity
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005975	biological_process	carbohydrate metabolic process
D	0006071	biological_process	glycerol metabolic process
D	0006072	biological_process	glycerol-3-phosphate metabolic process
D	0006641	biological_process	triglyceride metabolic process
D	0016301	molecular_function	kinase activity
D	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
D	0019563	biological_process	glycerol catabolic process
D	0046167	biological_process	glycerol-3-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 601

Chain	Residue
A	GLN83
A	ARG84
A	ASP254
A	GLN255

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE G3P B 601

Chain	Residue
B	GLN255
B	THR276
B	THR11
B	ARG84
B	GLU85
B	TRP104
B	ASP254

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE G3P C 701

Chain	Residue
C	THR11
C	ARG84
C	GLU85
C	TRP104
C	ASP254
C	GLN255
C	THR276
C	PHE279

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE G3P D 601

Chain	Residue
D	THR11
D	GLN83
D	ARG84
D	GLU85
D	TRP104
D	ASP254
D	GLN255
D	THR276
D	PHE279

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Functional Information from PROSITE/UniProt

site_id	PS00445
Number of Residues	21
Details	FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GtIVGMtlkttra.HVIRAALQ

Chain	Residue	Details
A	GLY373-GLN393

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