3WWI
Crystal structure of the G136F mutant of the first R-stereoselective -transaminase identified from Arthrobacter sp. KNK168 (FERM-BP-5228)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0046394 | biological_process | carboxylic acid biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0046394 | biological_process | carboxylic acid biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0019752 | biological_process | carboxylic acid metabolic process |
| C | 0046394 | biological_process | carboxylic acid biosynthetic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0019752 | biological_process | carboxylic acid metabolic process |
| D | 0046394 | biological_process | carboxylic acid biosynthetic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0019752 | biological_process | carboxylic acid metabolic process |
| E | 0046394 | biological_process | carboxylic acid biosynthetic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0019752 | biological_process | carboxylic acid metabolic process |
| F | 0046394 | biological_process | carboxylic acid biosynthetic process |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0019752 | biological_process | carboxylic acid metabolic process |
| G | 0046394 | biological_process | carboxylic acid biosynthetic process |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0019752 | biological_process | carboxylic acid metabolic process |
| H | 0046394 | biological_process | carboxylic acid biosynthetic process |
| I | 0003824 | molecular_function | catalytic activity |
| I | 0019752 | biological_process | carboxylic acid metabolic process |
| I | 0046394 | biological_process | carboxylic acid biosynthetic process |
| J | 0003824 | molecular_function | catalytic activity |
| J | 0019752 | biological_process | carboxylic acid metabolic process |
| J | 0046394 | biological_process | carboxylic acid biosynthetic process |
| K | 0003824 | molecular_function | catalytic activity |
| K | 0019752 | biological_process | carboxylic acid metabolic process |
| K | 0046394 | biological_process | carboxylic acid biosynthetic process |
| L | 0003824 | molecular_function | catalytic activity |
| L | 0019752 | biological_process | carboxylic acid metabolic process |
| L | 0046394 | biological_process | carboxylic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | ARG86 |
| A | THR282 |
| A | THR283 |
| A | HOH517 |
| A | HOH519 |
| A | HOH528 |
| A | HOH543 |
| A | LYS188 |
| A | GLU221 |
| A | PHE225 |
| A | ASN226 |
| A | LEU243 |
| A | GLY245 |
| A | ILE246 |
| A | THR247 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 188 |
| Chain | Residue |
| B | THR66 |
| B | TYR67 |
| B | ARG86 |
| B | ASN90 |
| B | VAL187 |
| B | ASN189 |
| B | GLU221 |
| B | GLY224 |
| B | PHE225 |
| B | ASN226 |
| B | LEU243 |
| B | GLY245 |
| B | ILE246 |
| B | THR247 |
| B | THR282 |
| B | THR283 |
| B | HOH506 |
| B | HOH530 |
| B | HOH532 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP C 401 and LYS C 188 |
| Chain | Residue |
| C | THR66 |
| C | TYR67 |
| C | ARG86 |
| C | ASN90 |
| C | VAL187 |
| C | ASN189 |
| C | GLU221 |
| C | PHE225 |
| C | ASN226 |
| C | LEU243 |
| C | GLY245 |
| C | ILE246 |
| C | THR247 |
| C | THR282 |
| C | THR283 |
| C | HOH513 |
| C | HOH515 |
| C | HOH587 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP D 401 and LYS D 188 |
| Chain | Residue |
| D | THR66 |
| D | TYR67 |
| D | ARG86 |
| D | ASN90 |
| D | VAL187 |
| D | ASN189 |
| D | GLU221 |
| D | GLY224 |
| D | PHE225 |
| D | ASN226 |
| D | LEU243 |
| D | GLY245 |
| D | ILE246 |
| D | THR247 |
| D | THR282 |
| D | THR283 |
| D | HOH503 |
| D | HOH512 |
| D | HOH519 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP E 401 and LYS E 188 |
| Chain | Residue |
| E | THR66 |
| E | TYR67 |
| E | ARG86 |
| E | ASN90 |
| E | VAL187 |
| E | ASN189 |
| E | GLU221 |
| E | PHE225 |
| E | ASN226 |
| E | LEU243 |
| E | GLY245 |
| E | ILE246 |
| E | THR247 |
| E | THR282 |
| E | THR283 |
| E | HOH515 |
| E | HOH522 |
| E | HOH578 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP F 401 and LYS F 188 |
| Chain | Residue |
| F | GLY245 |
| F | ILE246 |
| F | THR247 |
| F | THR282 |
| F | THR283 |
| F | HOH512 |
| F | HOH515 |
| F | HOH539 |
| F | THR66 |
| F | TYR67 |
| F | ARG86 |
| F | ASN90 |
| F | VAL187 |
| F | ASN189 |
| F | GLU221 |
| F | PHE225 |
| F | ASN226 |
| F | LEU243 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP G 401 and LYS G 188 |
| Chain | Residue |
| G | THR66 |
| G | TYR67 |
| G | ARG86 |
| G | ASN90 |
| G | VAL187 |
| G | ASN189 |
| G | GLU221 |
| G | GLY224 |
| G | PHE225 |
| G | ASN226 |
| G | LEU243 |
| G | GLY245 |
| G | ILE246 |
| G | THR247 |
| G | THR282 |
| G | THR283 |
| G | HOH507 |
| G | HOH508 |
| G | HOH521 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP H 401 and LYS H 188 |
| Chain | Residue |
| H | THR66 |
| H | TYR67 |
| H | ARG86 |
| H | ASN90 |
| H | VAL187 |
| H | ASN189 |
| H | GLU221 |
| H | GLY224 |
| H | PHE225 |
| H | LEU243 |
| H | GLY245 |
| H | ILE246 |
| H | THR247 |
| H | THR282 |
| H | THR283 |
| H | HOH501 |
| H | HOH517 |
| H | HOH582 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP I 401 and LYS I 188 |
| Chain | Residue |
| I | THR66 |
| I | TYR67 |
| I | ARG86 |
| I | ASN90 |
| I | VAL187 |
| I | ASN189 |
| I | GLU221 |
| I | GLY224 |
| I | PHE225 |
| I | ASN226 |
| I | LEU243 |
| I | GLY245 |
| I | ILE246 |
| I | THR247 |
| I | THR282 |
| I | THR283 |
| I | HOH503 |
| I | HOH527 |
| I | HOH565 |
| site_id | AD1 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP J 401 and LYS J 188 |
| Chain | Residue |
| J | THR66 |
| J | TYR67 |
| J | ARG86 |
| J | ASN90 |
| J | VAL187 |
| J | ASN189 |
| J | GLU221 |
| J | GLY224 |
| J | PHE225 |
| J | ASN226 |
| J | LEU243 |
| J | GLY245 |
| J | ILE246 |
| J | THR247 |
| J | THR282 |
| J | THR283 |
| J | HOH504 |
| J | HOH510 |
| J | HOH534 |
| site_id | AD2 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP K 401 and LYS K 188 |
| Chain | Residue |
| K | THR66 |
| K | TYR67 |
| K | ARG86 |
| K | ASN90 |
| K | VAL187 |
| K | ASN189 |
| K | GLU221 |
| K | PHE225 |
| K | ASN226 |
| K | LEU243 |
| K | GLY245 |
| K | ILE246 |
| K | THR247 |
| K | THR282 |
| K | THR283 |
| K | HOH515 |
| K | HOH517 |
| K | HOH545 |
| site_id | AD3 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP L 401 and LYS L 188 |
| Chain | Residue |
| L | THR66 |
| L | TYR67 |
| L | ARG86 |
| L | ASN90 |
| L | VAL187 |
| L | ASN189 |
| L | GLU221 |
| L | GLY224 |
| L | PHE225 |
| L | ASN226 |
| L | LEU243 |
| L | GLY245 |
| L | ILE246 |
| L | THR247 |
| L | THR282 |
| L | THR283 |
| L | HOH503 |
| L | HOH531 |
