3WTK

Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Thiacloprid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005576	cellular_component	extracellular region
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0043083	cellular_component	synaptic cleft
A	0045202	cellular_component	synapse
A	0098794	cellular_component	postsynapse
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005576	cellular_component	extracellular region
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0043083	cellular_component	synaptic cleft
B	0045202	cellular_component	synapse
B	0098794	cellular_component	postsynapse
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005576	cellular_component	extracellular region
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0043083	cellular_component	synaptic cleft
C	0045202	cellular_component	synapse
C	0098794	cellular_component	postsynapse
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005576	cellular_component	extracellular region
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0043083	cellular_component	synaptic cleft
D	0045202	cellular_component	synapse
D	0098794	cellular_component	postsynapse
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005576	cellular_component	extracellular region
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0043083	cellular_component	synaptic cleft
E	0045202	cellular_component	synapse
E	0098794	cellular_component	postsynapse

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TH4 B 301

Chain	Residue
A	TRP143
B	MET114
A	THR144
A	TYR185
A	CYS187
A	TYR192
B	TRP53
B	ARG104
B	LEU112
B	TYR113

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TH4 C 301

Chain	Residue
B	TRP143
B	TYR185
B	CYS187
B	TYR192
C	LYS34
C	TRP53
C	ARG104
C	LEU112
C	TYR113
C	MET114
C	HOH402

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TH4 D 301

Chain	Residue
C	TRP143
C	THR144
C	TYR185
C	CYS187
C	TYR192
D	TRP53
D	ARG104
D	LEU112
D	TYR113
D	MET114
D	HOH401
D	HOH446

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TH4 E 301

Chain	Residue
D	TRP143
D	TYR185
D	CYS187
D	TYR192
E	TRP53
E	ARG104
E	LEU112
E	MET114
E	HOH401
E	HOH482

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TH4 A 301

Chain	Residue
A	TRP53
A	ARG104
A	LEU112
A	MET114
A	HOH433
E	TRP143
E	THR144
E	TYR185
E	CYS187
E	TYR192

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305

Chain	Residue	Details
A	ASP66
B	ASP66
C	ASP66
D	ASP66
E	ASP66

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