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3WTI

Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Clothianidin

Functional Information from GO Data
ChainGOidnamespacecontents
A0004888molecular_functiontransmembrane signaling receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
A0005576cellular_componentextracellular region
A0006811biological_processmonoatomic ion transport
A0007165biological_processsignal transduction
A0007268biological_processchemical synaptic transmission
A0016020cellular_componentmembrane
A0034220biological_processmonoatomic ion transmembrane transport
A0042391biological_processregulation of membrane potential
A0043005cellular_componentneuron projection
A0043083cellular_componentsynaptic cleft
A0045202cellular_componentsynapse
A0050877biological_processnervous system process
A0060078biological_processregulation of postsynaptic membrane potential
A0060079biological_processexcitatory postsynaptic potential
A0098794cellular_componentpostsynapse
A1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B0004888molecular_functiontransmembrane signaling receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
B0005576cellular_componentextracellular region
B0006811biological_processmonoatomic ion transport
B0007165biological_processsignal transduction
B0007268biological_processchemical synaptic transmission
B0016020cellular_componentmembrane
B0034220biological_processmonoatomic ion transmembrane transport
B0042391biological_processregulation of membrane potential
B0043005cellular_componentneuron projection
B0043083cellular_componentsynaptic cleft
B0045202cellular_componentsynapse
B0050877biological_processnervous system process
B0060078biological_processregulation of postsynaptic membrane potential
B0060079biological_processexcitatory postsynaptic potential
B0098794cellular_componentpostsynapse
B1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C0004888molecular_functiontransmembrane signaling receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
C0005576cellular_componentextracellular region
C0006811biological_processmonoatomic ion transport
C0007165biological_processsignal transduction
C0007268biological_processchemical synaptic transmission
C0016020cellular_componentmembrane
C0034220biological_processmonoatomic ion transmembrane transport
C0042391biological_processregulation of membrane potential
C0043005cellular_componentneuron projection
C0043083cellular_componentsynaptic cleft
C0045202cellular_componentsynapse
C0050877biological_processnervous system process
C0060078biological_processregulation of postsynaptic membrane potential
C0060079biological_processexcitatory postsynaptic potential
C0098794cellular_componentpostsynapse
C1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D0004888molecular_functiontransmembrane signaling receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
D0005576cellular_componentextracellular region
D0006811biological_processmonoatomic ion transport
D0007165biological_processsignal transduction
D0007268biological_processchemical synaptic transmission
D0016020cellular_componentmembrane
D0034220biological_processmonoatomic ion transmembrane transport
D0042391biological_processregulation of membrane potential
D0043005cellular_componentneuron projection
D0043083cellular_componentsynaptic cleft
D0045202cellular_componentsynapse
D0050877biological_processnervous system process
D0060078biological_processregulation of postsynaptic membrane potential
D0060079biological_processexcitatory postsynaptic potential
D0098794cellular_componentpostsynapse
D1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
E0004888molecular_functiontransmembrane signaling receptor activity
E0005216molecular_functionmonoatomic ion channel activity
E0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
E0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
E0005576cellular_componentextracellular region
E0006811biological_processmonoatomic ion transport
E0007165biological_processsignal transduction
E0007268biological_processchemical synaptic transmission
E0016020cellular_componentmembrane
E0034220biological_processmonoatomic ion transmembrane transport
E0042391biological_processregulation of membrane potential
E0043005cellular_componentneuron projection
E0043083cellular_componentsynaptic cleft
E0045202cellular_componentsynapse
E0050877biological_processnervous system process
E0060078biological_processregulation of postsynaptic membrane potential
E0060079biological_processexcitatory postsynaptic potential
E0098794cellular_componentpostsynapse
E1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE CT4 A 301
ChainResidue
ATRP143
ATYR185
ACYS187
ATYR192
BTRP53
BARG104
BLEU112
BMET114
BHOH434

site_idAC2
Number of Residues14
DetailsBINDING SITE FOR RESIDUE CT4 B 301
ChainResidue
BTYR89
BTRP143
BTYR185
BCYS187
BTYR192
CLYS34
CTRP53
CARG55
CLEU102
CALA103
CARG104
CLEU112
CMET114
CHOH426

site_idAC3
Number of Residues12
DetailsBINDING SITE FOR RESIDUE CT4 C 301
ChainResidue
CTRP143
CTYR185
CCYS187
CTYR192
CHOH413
CHOH427
CHOH429
DTRP53
DARG55
DARG104
DLEU112
DMET114

site_idAC4
Number of Residues11
DetailsBINDING SITE FOR RESIDUE CT4 D 301
ChainResidue
DTRP143
DTYR185
DCYS187
DTYR192
DHOH431
ETRP53
EARG55
EARG104
ELEU112
EMET114
EHOH402

site_idAC5
Number of Residues11
DetailsBINDING SITE FOR RESIDUE CT4 E 301
ChainResidue
ATRP53
AARG55
AARG104
ALEU112
AMET114
AHOH428
ETRP143
ETYR185
ECYS187
ETYR192
EHOH440

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305
ChainResidueDetails
AASP66
BASP66
CASP66
DASP66
EASP66

224201

PDB entries from 2024-08-28

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