Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003756 | molecular_function | protein disulfide isomerase activity |
B | 0003756 | molecular_function | protein disulfide isomerase activity |
C | 0003756 | molecular_function | protein disulfide isomerase activity |
Functional Information from PROSITE/UniProt
site_id | PS00194 |
Number of Residues | 19 |
Details | THIOREDOXIN_1 Thioredoxin family active site. LIeFYapWCGHCKaLapkY |
Chain | Residue | Details |
A | LEU357-TYR375 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: Nucleophile => ECO:0000250 |
Chain | Residue | Details |
A | CYS365 | |
A | CYS368 | |
B | CYS365 | |
B | CYS368 | |
C | CYS365 | |
C | CYS368 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | SITE: Contributes to redox potential value => ECO:0000250 |
Chain | Residue | Details |
A | GLY366 | |
A | HIS367 | |
B | GLY366 | |
B | HIS367 | |
C | GLY366 | |
C | HIS367 | |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | SITE: Lowers pKa of C-terminal Cys of second active site => ECO:0000250 |
Chain | Residue | Details |
A | ARG431 | |
B | ARG431 | |
C | ARG431 | |